COURSE UNIT TITLE

: MOLECULAR CELL BIOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TBG 6091 MOLECULAR CELL BIOLOGY ELECTIVE 4 0 0 12

Offered By

The Institute Of Health Sciences

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR SEFA KIZILDAĞ

Offered to

Medical Biology and Genetics

Course Objective

Covering in detail the molecular structure and function of cells. Cell to cell and cell to environment (e.g. ECM) interactions. Covering the cellular signalling pathways and homeostasis and death mechanisms.

Learning Outcomes of the Course Unit

1   Understanding the detailed structure of prokaryotic and eukaryotic cells at physical and chemical level.
2   Understanding the interrelationship of living cells.
3   Understanding the communication of cell with its environment.
4   Understanding the intracellular metabolic events and energetic transformations.
5   Understanding the cellular genome structures and genetic activities.
6   Understanding the differentiation, proliferation and death of cells.
7   Learning the immune system cells and their genomes.
8   Capability of analyzing and interpreting the knowledge.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Cell Theory. Why cells are microscopic in size Definition of Life. Eukaryotic and Prokaryotic cell types, structural, evolutional and genomic features.
2 Molecular substructure of cells. Polymers and monomers of building blocks. Cell analysing techniques
3 Amino acids, protein structure, chemical features and interactions with other molecules. Cell membrane and cell wall; structures and features.
4 Structure and features of extra cellular matrix. Mitosis, meiosis and gametogenesis.
5 Bio energetic principles. Roles of mitochondria, chloroplast and peroxisomes. Cell chemistry and Metabolism I
6 Cell chemistry and Metabolism II. Cellular life Cycle and its regulation.
7 Genome organizations of prokaryotic and Eukaryotic cells. Intracellular membranes, cell skeleton and intracellular trafficking.
8 DNA replication, repair and mutations.
9 DNA replication, repair and mutations.
10 RNA synthesis and Processing.
11 Protein synthesis and its control. Micro RNAs.
12 Cellular movements, intercellular communications. Cell signalling.
13 Fertilization, cellular differentiation and organogenesis.
14 Protein sorting and transport: Endoplasmic reticulum, Golgi, Lysosomes.
15 Types and features of immune system cells.
16 Cellular aging and cell death

Recomended or Required Reading

Textbook(s): Alberts et al., Molecular Biology of The Cell, 2008
Pollard TD, Earnshaw WC. Cell Biology, SAUNDERS Elsevier, 2008
Snyder L & Champness W. Molecular Genetics of Bacteria. ASM Press. 2007
References: Up to date review/ research articles from journals with high impact factors.

Planned Learning Activities and Teaching Methods

Oral Presentation: Basic information, especially the subjects that are hard to understand or unreachable will be given by tutor.
Article Discussion: Some up to date articles related to the basic subjects will be chosen and students will be asked to read and discuss.
Home Work: Several questions aiming to increase the synthesis and analysis abilities of students will be given and asked for a written report.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 + FIN* 0.60
5 RST RESIT
6 FCGR FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 +RST* 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

Written Exams: At least 75% of questions should be answered correctly.
Home Works: By assessing the student s accuracy of approach, ability of observation and analysis and the originality of answers at least 75% shell be the success criteria.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Tlf: 232. 4613 or 232.4601
sefa.kizildag@deu.edu.tr

Office Hours

week day 12.30-13:30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 4 60
Preparations before/after weekly lectures 15 5 75
Preparation for midterm exam 1 10 10
Preparation for final exam 1 10 10
Preparation for quiz etc. 2 10 20
Preparing Individual Assignments 5 5 25
Preparing Presentations 5 5 25
manuscript preparation 7 9 63
Final 1 3 3
Midterm 1 3 3
Quiz etc. 2 3 6
TOTAL WORKLOAD (hours) 300

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9
LO.11
LO.21
LO.31
LO.41
LO.512
LO.612
LO.712
LO.845

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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