COURSE UNIT TITLE

: CELL MEMBRANE SYSTEMS IN EUKARYOTES

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TBG 6102 CELL MEMBRANE SYSTEMS IN EUKARYOTES ELECTIVE 2 0 0 6

Offered By

Medical Biology and Genetics

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR SAFIYE NEŞE ATABEY

Offered to

Medical Biology and Genetics

Course Objective

Learning the detailed structures of cellular membranes, their permeability characteristics, intra-intercellular associations of membrane proteins and the transport systems.

Learning Outcomes of the Course Unit

1   Understanding the detailed structure and biochemical characteristics of eukaryote cells.
2   Understanding the membrane proteins, their mission and cellular interactions.
3   Understanding the dynamics of intracellular membranes, ER, Golgi, lysosomes and nuclear envelope.
4   Understanding the active and passive transport through membranes and endocytosis.
5   Understanding the roles of membranes in protein sorting and signaling.
6   Understanding the membrane transporters and chaperones.
7   Understanding the membrane specifications of mitochondria, chloroplast and peroxysomes and the energetic reactions.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 General Structure of Cellular Membranes and Biochemical Features
2 Penetration Characteristics and Physiology of Membranes
3 Membrane Proteins, their Missions and Skeletal Attachments
4 Dynamics of Membranes., ER, Golgi, Lysosomes
5 Structure of Nuclear Envelope, Penetration Characteristics and Nuclear Pores
6 Active and Passive Transport Through Membranes
7 Membrane Plasticity in Endocytic Process and the Cytoplasmic events
8 Some Important Active and Passive Transport Events in Organisms
9 Role and Importance of Cellular Membranes in the Generation of Chemical and Electrical Gradients
10 Membrane Specifications of Mitochondria, Chloroplast and Peroxysomes and Energetic Reactions.
11 Roles of Membranes in Protein Sorting and Signaling
12 Membrane Transporters and Chaperon Molecules
13 GENERAL DISCUSSION
14 HOME WORK DISCUSSION
15 FINAL EXAM

Recomended or Required Reading

Textbook(s): Alberts et al., Molecular Biology of The Cell, 2008
Pollard TD, Earnshaw WC. Cell Biology, SAUNDERS Elsevier, 2008
Snyder L & Champness W. Molecular Genetics of Bacteria. ASM Press. 2007
References: Up to date review/ research articles from journals with high impact factors.

Planned Learning Activities and Teaching Methods

Oral Presentation: Basic information, especially the subjects that are hard to understand or unreachable will be given via slide presentations.
Interactive Teaching: Students will be asked to study special subjects that will be discussed together
Article Discussion: Some up to date articles related to the basic subjects will be chosen and students will be asked to read and discuss.
Home Work: To improve their analysis ad synthesis abilities, students will be given some questions to investigate, interpret and asked to prepare a written report.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 +PRF * 0.30 + FIN* 0.50
5 RST RESIT
6 FCGR FINAL COURSE GRADE MTE * 0.20 +PRF * 0.30 +RST* 0.50

Further Notes About Assessment Methods

If the instructor needs to add some explanation or further note, this column can be selected from the DEBIS menu.

Assessment Criteria

Written Exams: At least 75% of questions should be answered correctly.
Home Works: By assessing the student s accuracy of approach, ability of observation and analysis and the originality of answers at least 75% shell be the success criteria.

Language of Instruction

Turkish

Course Policies and Rules

Student's participation and fulfilment of expectations will be our policy.

Contact Details for the Lecturer(s)

Tlf: 232. 4646 or 232.4601
meral.sakizli@deu.edu.tr

Office Hours

From Monday to Friday at 12:00-13:00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Preparation for final exam 1 10 10
Preparation before/after weekly lectures 15 1 15
Preparation for midterm exam 1 10 10
Preparing Individual Assignments 6 6 36
Preparing presentations 3 6 18
Other (Articles) 5 5 25
Final 1 3 3
Midterm 1 3 3
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9
LO.11345
LO.21345
LO.31345
LO.41345
LO.51345
LO.61345
LO.71345

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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