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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS MIK 6039 INFECTION AND PATHOGENESIS ELECTIVE 4 0 0 12

Offered By

Microbiology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR ZEYNEP GÜLAY

Offered to

Microbiology

Course Objective

Comprehend the interaction between the host and microbes in infectious disease pathogenesis by molecular and cellular level upon the certain disease and micrope models

Learning Outcomes of the Course Unit

1   Understand the concepts of colonization, infection and virulan and also learn the way of define virulans factors 2   Identification of the basic mechanisms of host defense against infection 3   Identify bacterial virulence factors 4   Identify of virulence factors in the pathogenesis of bacterial infection and immune response in the context of models for the location of the disease 5   Understand virulence factors involved in the pathogenesis of fungal diseases and identification of antifungal immune components 6   Define the association between the virus-cell interactions and pathogenesis 7   Define the natural and adapted immun system in take a role of antiviral responses 8   Define the concepts of presitancy, latency and oncogenesis

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Basic concepts related to bacterial infections 2 Defense mechanisms against infections 3 Bacterial virulance factors-I 4 Bacterial virulance factors-II 5 Pathogenesis of bacterial diseases in various models 6 Fungal virulance factors 7 Immunity to fungal infections 8 Pathogenesis of oppurtunistic fungal infections 9 Pathogenesis of systemic fungal infections 10 Virus-cell interaction: replication cycle 11 Host response in viral infection, latency and persistancy mechanisms 12 viral oncogenesis

Recomended or Required Reading

Wilson AB, salyers AA, Whitt DD, Winkler ME Bacterial pathogenesis : A molecular approach 3rd ed. ASM Press Washington DC, 2011 Abbas, Lichtman & Pillai. Cellular and Molecular Immunology 7th Ed, Saunders, Elsevier, 2012

Planned Learning Activities and Teaching Methods

Theoretical lessons and practices, as well as one of the selected article by the instructor for that year are examined in detail and presented.

Assessment Methods

Successful / Unsuccessful

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

zeynep.gulay@deu.edu.tr,zeynepgulay62@gmail.com

Office Hours

Thursday 14:30-16:30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 30 2 60 Case study 30 1 30 Student Presentations 1 2 2 Field study 1 16 16 Preparing assignments 30 2 60 Web Search and Library Research 30 2 60 Reading 6 3 18 Preparation for final exam 1 24 24 Preparing presentations 1 16 16 Final 1 2 2 TOTAL WORKLOAD (hours) 288

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 PO.11 PO.12 LO.1 5 4 2 2 2 2 3 2 LO.2 5 4 3 5 3 2 2 3 2 LO.3 5 4 3 2 2 2 2 3 2 LO.4 5 4 3 2 2 5 3 2 2 3 2 LO.5 5 4 3 3 2 2 3 2 LO.6 5 4 2 3 3 2 2 3 2 LO.7 5 LO.8 3 3 2 2 3 2