COURSE UNIT TITLE

: THE BIOLOGY OF TUMOR AND METASTASIS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 6080 THE BIOLOGY OF TUMOR AND METASTASIS ELECTIVE 1 0 0 3

Offered By

Basic Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR SAFIYE AKTAŞ

Offered to

Basic Oncology

Course Objective

The aim of this course is to understand the biology of cancer, angiogenesis, invasion and metastasis and their clinical view.

Learning Outcomes of the Course Unit

1   Capable of understanding molecular biologic properties of tumors; nature of metastasis
2   Be able to explain cancer from molecule to cell and from cell to tissue
3   Be able to know cell adhesion molecules and their roles in cancer
4   Be able to learn role of angiogenesis and lymphangiogenesis in cancer
5   Be able to understand stages of metastasis and metastasis related genes

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Differences of cancer cell from normal cell
2 Cancer from molecule to cell and from cell to tissue
3 Properties of cell membrane
4 Changes in cell membrane in cancer
5 Cross talk between cells
6 Crosstalk changes between cells in cancer tissue
7 Transport in cancer cell and changes in protein trafficing
8 Relationship of singalling pathways special for embriogenesis and cancer
9 Cell adhesion molecules and cancer
10 Angiogenesis and lymphangiogenesis

Recomended or Required Reading

1. Diagnostic Approach to Clinical Oncology Mario W. Fiorentino PICCIN 1999
2. Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995.
3. AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins 1998
4. Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 1990 Fith Edition.
5. Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
6. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
7. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007

Planned Learning Activities and Teaching Methods

Theoretical Lectures, Giving a homework, Working for exams, Reading practices

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PO * 0.40 + FN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PO * 0.40 + BUT*0.60

Further Notes About Assessment Methods

None

Assessment Criteria

Learning outcomes will be assessed with classical questions of mid-term and final exams. The homework on the topic of reading and evaluating 5 different types of papers will help in evaluating the learner understood the topics or not.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

safiye.aktas@deu.edu.tr 0 232 4125891/5801

Office Hours

on Monday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 1 15
Preparation before/after weekly lectures 15 1 15
Preparation for Final Exam 1 20 20
Preparing Individual Assignments 1 20 20
Final 1 4 4
TOTAL WORKLOAD (hours) 74

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.155
LO.255
LO.355
LO.455
LO.555

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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