COURSE UNIT TITLE

: THE BIOLOGY OF CANCER STEM CELL

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 6092 THE BIOLOGY OF CANCER STEM CELL ELECTIVE 1 0 0 3

Offered By

Basic Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR SAFIYE AKTAŞ

Offered to

Basic Oncology

Course Objective

The aim of this course is to understand the biology, molecular properties and genetics of cancer stem cell in a translational overview.

Learning Outcomes of the Course Unit

1   Capable of understanding cancer stem cell and its clinical role
2   Be able to explain sharing and different properties of cancer stem cell and normal stem cell
3   Be able to learn role of cancer stem cell in cancer development
4   Be able to know cancer stem cell related signalling pathways, role of stem cell in hematologic and solid cancers
5   Be able to explain cancer stem cell as a therapoetic target
6   Be able to do cancer stem cell isolation and identification

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Defination and morphology of stem cell
2 Properties of cancer stem cell
3 Cancer stem cell role in cancer development
4 Signalling pathways in cancer stem cell
5 Role of cancer stem cell in hematopoetic cancers
6 Role of cancer stem cell in pediatric cancers
7 Role of cancer stem cell in adult solidc cancers
8 Role of cancer stem cell in therapy resistance
9 Stem cell biomarkers
10 Methods of stem cell isolation and identification

Recomended or Required Reading

: 1. Diagnostic Approach to Clinical Oncology Mario W. Fiorentino PICCIN 1999
2. Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995.
3. AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins 1998
4. Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 1990 Fith Edition.
5. Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
6. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
7. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007

Planned Learning Activities and Teaching Methods

Theoretical Lectures, Giving a homework, Working for exams, Reading practices

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 + FIN* 0.60
5 RST RESIT
6 FCGR FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 +RST* 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

Learning outcomes will be assessed with classical questions of mid-term and final exams. The homework on the topic of reading and evaluating 5 different types of papers will help in evaluating the learner understood the topics or not.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

safiye.aktas@deu.edu.tr 0 232 4125891/5801

Office Hours

on Monday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 1 14
Preparation before/after weekly lectures 14 1 14
Preparation for Final Exam 1 22 22
Preparing Individual Assignments 1 22 22
Final 1 3 3
TOTAL WORKLOAD (hours) 75

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.15
LO.25
LO.35
LO.45
LO.55
LO.65

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

Copyright 2015 DEÜ. BİD

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