COURSE UNIT TITLE

: ADVANCED RESEARCH METHODS IN CANCER II

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 6082 ADVANCED RESEARCH METHODS IN CANCER II ELECTIVE 1 2 0 6

Offered By

Basic Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR YASEMIN BASKIN

Offered to

Basic Oncology

Course Objective

The aim of this course the acquisition of basic knowledge about cancer research laboratory by translational perspective (bed to bench, bench to bed) , introduce new technologies and related multidisciplinary laboratory methods and thus their thesis and research projects associated with analytical studies will continue.

Learning Outcomes of the Course Unit

1   Be able to Applies advanced molecular methods for advanced cancer research.
2   Be able to know methods for distinguishing individual differences.
3   Be able to critically evaluates the published literature in the field of cancer research and adapt their own applications
4   Be able to know cancer treatment technologies
5   Be able to know methods for identify cancer at the molecular level.
6   Acquire basic knowledge of the basic principles of cancer research laboratory

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Course description and general concepts
2 Research methods in preventive oncology (identification of individuals at risk for cancer, screening programs and tests, environmental carcinogenesis, Nutrigenomics, population genetics)
3 The research methods in clinical oncology (diagnostic tumor markers)
4 The research methods in clinical oncology (predictive tumor markers)
5 Tumor models (in vivo (animal experiments) in vitro (tissue culture), exvivo models)
6 Biobanking on cancer research
7 Basic research methods in oncology (basic laboratory principles)
8 Basic research methods in oncology (basic techniques)
9 Cell culture and related methods in cancer research
10 Advanced molecular methods in cancer research, (hybridization, FISH, flow cytometry, etc.)
11 Advanced molecular methods in cancer research (genomics, proteomics, metabolamics, systems biology)
12 Advanced molecular methods in cancer research (molecular cloning, DNA sequencing)
13 Treatment technologies in cancer research, (research on treatment techniques, recombinant protein technology)
14 Treatment technologies in cancer research, (nanobiotechnology, drug design,)
15 Treatment technologies in cancer research, (pharmacogenomics studies, cancer vaccines, cellular modulations)

Recomended or Required Reading

Textbook(s):
1.Tumor Models in Cancer Research, Beverly A. Teicher Humana Pres 2002
2.Culture of Animal Cells R. Ian Freshney Wiley-Liss 2000 Fourth Edition
3.Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
4.Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
5.The Biology of Cancer Robert A. Weinberg, Gariand Science 2007
6.Baxevanis, A.D. and Ouellette, B.F.F., eds., Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, third edition. Wiley, 2005.
7.Kohane, et al. Microarrays for an Integrative Genomics. The MIT Press, 2002.

Planned Learning Activities and Teaching Methods

Theoretical and applied Lectures, the topics in-class activities (presentations and assignments) to consolidate and discussion, laboratory applications, and application assignments

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PO * 0.40 + FN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PO * 0.40 + BUT*0.60

Further Notes About Assessment Methods

None

Assessment Criteria

Learning outcomes, intermediate and long-answer questions will be evaluated with classical written final exam. Strengthened by homework. Midterm exam will consist of half of the evaluation of laboratory applications

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

yasemin.baskin@deu.edu.tr 0 232 4125890/5801

Office Hours

Monday 12.30-13.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 1 15
Tutorials 15 2 30
Preparations before/after weekly lectures 5 5 25
Preparation for midterm exam 1 23 23
Preparation for final exam 1 35 35
Preparing assignments 1 20 20
Final 1 1 1
Midterm 1 1 1
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.155
LO.2555555
LO.3555
LO.4555
LO.5555
LO.65555