COURSE UNIT TITLE

: CELLULAR AND GENE THERAPY IN ONCOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 6103 CELLULAR AND GENE THERAPY IN ONCOLOGY ELECTIVE 1 0 0 3

Offered By

Basic Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR ZEKIYE SULTAN ALTUN

Offered to

Basic Oncology

Course Objective

The aim of this course the acquisition of basic knowledge about the characteristics of molecular, biological and genetics of cellular and gene therapy related to clinical parameters in translational. Therefore, to get the basic knowledge about newly developed teharpautic approaches in cancer research in the field of cellular and gene therapy methods and gain the basic knowledge about the techniques and applications of gene therapy, cell and gene therapy to introduce the necessary tools and laboratory methods, whereby the cell and gene therapies are committed to containing the thesis and research projects.

Learning Outcomes of the Course Unit

1   Capable of outlined the celular and gene therapy methods in cancer can express
2   Be able to apply the basic methods of celular and gene therapies in cancer
3   Be able to recognize and understand the types of celular and gene therapies
4   Be able to identify of celular and gene therapies in cancer and interpret
5   Be able to research and inquire about the work of celular and gene therapies in cancer

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to cellular and gene therapy
2 Methods of Gene Transfer
3 Gene Marking Studies
4 Genetic Modification of the Immune Response
5 Modification of Tumors with Genes That Have Direct Antitumor Effects
6 Selective Replication of Virus in Tumors
7 Introduction of Genes into Normal Tissues to Protect Them from Chemotherapy or Radiotherapy
8 Antiangiogenic Gene Therapy
9 Molecular Imaging of Gene-Modified Cells
10 Immunotherapy mechanisms
11 Dendritic cell therapies in cancer
12 Tumor vaccines
13 Cellular and gene therapies in Hematologic malignancies
14 Cellular and gene therapies in solid malignancies
15 Presentations of projects

Recomended or Required Reading

.Principles and Practise of Oncology 7th edition. Vincent T De Vita 2005.
2. Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995.
3. AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins 1998
4. Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 1990 Fith Edition.
5. Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
6. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
7. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007

Planned Learning Activities and Teaching Methods

Theoretical and applied Lectures, giving a homework and having a presentations.
Students will prepare homework related cellular and gene therapies of to lung, breast and colon cancer.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 SEM SEMINAR
3 FCG FINAL COURSE GRADE ASG * 0.40 + SEM * 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

1. The learner will clearly define outlined cellular and gene therapies which will evaluate with presentations prepared by themselves and homework.
2. The learner will recognize basic laboratory methods of cellular and gene therapies; will evaluate with homework, prepared presentations by themselves.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

zekiye.altun@deu.edu.tr 0 232 4128204/8204

Office Hours

on Tuesday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 16 1 16
Preparations before/after weekly lectures 16 1 16
Preparing assignments 1 30 30
Preparing presentations 1 13 13
TOTAL WORKLOAD (hours) 75

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.155555555
LO.2555555
LO.3555555
LO.455555555
LO.55555555555

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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