COURSE UNIT TITLE

: BIOCHEMICAL MECHANISM AND LABORATORY DIAGNOSIS OF NEUROPSYCHIATRIC DISEASE

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
SBI 6074 BIOCHEMICAL MECHANISM AND LABORATORY DIAGNOSIS OF NEUROPSYCHIATRIC DISEASE ELECTIVE 2 2 0 12

Offered By

Basic Neuroscience

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR PINAR AKAN

Offered to

Basic Neuroscience

Course Objective

The aim of this course is to discuss the biochemical structure of CNS and its roles in neuronal diseases, to learn biochemical mechanism and laboratory diagnosis of neuronal damage in neuropsychiatric disease.
In the practical related to the course, the following applications will be conducted: CSF biochemistry, cell counting, CSF IgG/IgM index, CSF oligoclonal band analysis and to interpret the other routine biochamical markers in CNS and psychiatric disorders.

Learning Outcomes of the Course Unit

1   Understand, at the introductory level, biochemical organization of central nervous system.
2   Have knowledge on ischemic damage mechanism of neuronal tissue.
3   Have knowledge on damage mechanism of neurodegenerative diseases.
4   Have knowledge on myelin damage mechanisms.
5   Have expertise in the theoretical basis of advance laboratory techniques in neurological diagnosis.
6   Have knowledge on neurotransmitters and cell membrane dysfunctions in psyciatric diseases.
7   Have knowledge on metabolic effects of alcohol usage in neuronal tissue.
8   Have knowledge on association between phytochemical agents and central nervous system diseases.
9   Understand, at introductory level, neuronal hormones and their functions.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Biochemical Organization of Neuronal Tissue I Blood brain barrier Biochemical structure
2 Biochemical Organization of Neuronal Tissue II The relation between neurological findings and metabolism
3 Biochemical Organization of Neuronal Tissue III Hormones
4 Damage Mechanism of CNS I Ischemic damage
5 Damage Mechanism of CNS II Myelin damage
6 Damage Mechanism of CNS III Neurodegenaration
7 Laboratory Diagnosis in Neurologic Disease I Biochemical markers Laboratory Practise
8 Damage Mechanism of CNS II CSF Biochemistry Laboratory Practise
9 Exam
10 The role of oxidative damage in neuropsychiatric diseases
11 Fitochemical agents and neuropsychiatry
12 Biochemical changes of cell membrane in cognitive dysfunctions and chronic alcohol usage
13 Neurotransmitters and psychiatric disorders
14 Biochemical results of acute and chronic alcohol usage in neuronal tissue

Recomended or Required Reading

1. Laboratory Diagnosis in Neurology, 2th Ed., 2010, Canada.
2. Basic Neurochemistry Molecular Cellular and Medical Aspects, 7th Ed., 2006 USA.
3. the Biochemical Basis of Neuropharmacology, 8th Ed., 2003, USA.

Planned Learning Activities and Teaching Methods

The course will be run in an integrated way-winding theory with case discussion and laboratory practicals. The methods of learning will be interactive.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE* 0.25 + ASG* 0.25 + FIN* 0.50
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE* 0.25 + ASG* 0.25 + RST* 0.50

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

The student is expected to read the resources before coming to class. In addition, he/she is expected to contribute actively to discussion, group-work, and practicals. Attending in at least 70 percent of lectures and in at least 80 percent of practicals are mandatory.
Plagiarism of any type will result in disciplinary action.

Contact Details for the Lecturer(s)

pinar.akan@deu.edu.tr
Phone: 412 25 52
GSM: +536 341 51 30

Office Hours

Every day, 12.30-13.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Tutorials 14 2 28
Preparations before/after weekly lectures 13 5 65
Preparation for midterm exam 1 25 25
Preparation for final exam 1 50 50
Preparing assignments 1 50 50
Preparing presentations 1 50 50
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 300

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14PO.15PO.16PO.17
LO.15
LO.24
LO.344
LO.445
LO.544445
LO.65
LO.7445
LO.844
LO.94

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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