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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS SBI 6076 BIOLOGY OF AGING AND DEMENTIA ELECTIVE 2 2 0 9

Offered By

Basic Neuroscience

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR ŞERMIN GENÇ

Offered to

Basic Neuroscience

Course Objective

Description of the biological processes and pathologies participating in aging and dementia

Learning Outcomes of the Course Unit

1   Learning biological processes in aging 2   Learning pathogenesis of dementia 3   Application of in vitro Amyloid toxicity method 4   Accessing and making sense of scientific knowledge 5   Having the ability of written and oral presentation

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Cell Senescence Mitochondrial aging Genetic changes as a result of aging In vitro amyloid toxicity study (LDH)-lab hour Article discussion 2 Alzheimer s disease pathogenesis In vitro amyloid toxicity study (LDH)-lab hour Genetics of Alzheimer s Article discussion 3 Changes in protein levels in Alzheimer s disease-lab hour Changes in mRNA levels in Alzheimer s disease-lab hour Changes in miRNA levels in Alzheimer s disease-lab hour Article discussion

Recomended or Required Reading

Textbook(s): Nature Review Neuroscience

Planned Learning Activities and Teaching Methods

Oral presentation, literature search

Assessment Methods

Successful / Unsuccessful

Further Notes About Assessment Methods

None

Assessment Criteria

Theoretical knowledge will be assessed by exam, accessing literature will be evaluated by journal club meetings.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

23588

Office Hours

Friday 16-17

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 30 1 30 Tutorials 30 1 30 Preparations before/after weekly lectures 13 7 91 Preparation for midterm exam 1 30 30 Preparation for final exam 1 40 40 Final 1 2 2 Midterm 1 2 2 TOTAL WORKLOAD (hours) 225

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 PO.11 PO.12 PO.13 PO.14 PO.15 PO.16 PO.17 LO.1 5 LO.2 5 LO.3 5 LO.4 5 LO.5 5