COURSE UNIT TITLE

: INTRODUCTION TO MOLECULAR MEDICINE

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MOT 5016 INTRODUCTION TO MOLECULAR MEDICINE COMPULSORY 3 0 0 6

Offered By

Molecular Medicine

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR GÜL HÜRAY IŞLEKEL

Offered to

Molecular Medicine

Course Objective

To understand cell behaviour at molecular level; to learn mutation, polymorphism, inheritance, fundamentals of single gene and chromosomal abnormalities, neoplasia, Mendelian and non-mendelian genetics, stem cell and applications of stem cells in molecular medicine.

Learning Outcomes of the Course Unit

1   To get know about human genome projects and contributions to medicine
2   To have general knowledge about bioinformatic databases and their usage
3   To be able to discuss general concepts of molecular genetics
4   To describe how to discover disease-related genes
5   To be able to discuss stem cells and stem cell-based therapies in medicine
6   To be able to discuss cancer mechanisms
7   To describe the roles of cell-cell, cell-ECM and niche on the disease formation and/or progression

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 History of Molecular Medicine
2 Human genome project and contributions to medicine Proteomics and applications
3 Bioinformatics tools (Entrez, Ensemble, OMIM, GSEE, PDB, Blaster, KEGG)
4 DNA, chromosome, chromatin structure and properties of chromosomal abnormalities, diseases
5 DNA replication, gene expression (transcription and translation), and its role in disease
6 Mutations definition, single-gene mutations, varieties, disease and polymorphism
7 Identification of disease-related genes
8 Determining DNA damage and repair mechanisms and methods
9 MID-TERM
10 Genetic and epigenetic control mechanisms
11 Cell-cell, cell-ECM interactions, and their relationship with diseases of microenvironments
12 Molecular basis of Immunology
13 Molecular basis of neoplasia
14 Fundamentals of Molecular Metabolism
15 final

Recomended or Required Reading

Lodish, Berk, Matsudaira, Kaiser, Krieger, Scott, Zipursky, Darnell , Molecular Cell Biology
Alberts, etal. Molecular Biology of the Cell , Fifth ed., Garland Sciences.

Planned Learning Activities and Teaching Methods

Course will be performed by a series of presentations which include theriotecal knowledge and related-examples with the subjects. It is accepted that students should read about presentation subjects before coming to classroom.
Methods: Interactive presentations

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE MTE * 0.40 + FIN* 0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE MTE * 0.40 + RST* 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

Understanding, learning, analyse, compare, actively contribution

Language of Instruction

Turkish

Course Policies and Rules

Actively contribution in class

Contact Details for the Lecturer(s)

e-posta: huray.islekel@deu.edu.tr
Telefon: 412 44 08

Office Hours

Salı 12.30-13:30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 3 42
Preparation for midterm exam 1 33 33
Preparation for final exam 1 33 33
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.155445545444445
LO.244445555544335
LO.355445555544555
LO.455445554444445
LO.555555555544545
LO.655555555544445
LO.755555555544445

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

Copyright 2015 DEÜ. BİD

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