Dokuz Eylül University Information Package / Courses Catalog

Description of Individual Course Units

Course Unit Code	Course Unit Title	Type Of Course	D	U	L	ECTS
MOT 6033	OXIDATIVE STRESS, FREE RADICALS AND ANTIOXIDANT DEFENSE	ELECTIVE	2	2	0	9

Offered By

Molecular Medicine

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR ZAHIDE ÇAVDAR

Offered to

Molecular Medicine

Course Objective

The purpose of this course is to learn types and formation of free radicals and also damages on biomolecules resulted from free radicals. In parallel, it involves the antioxidant defense system. The role of oxidative stress in the formation of various disease will be discussed. In the practise session of this course, techniques using in the detection of oxidant and antioxidant parameters will be performed in the laboratory.

Learning Outcomes of the Course Unit

1	Define the term free radical and explain the types and sources of free radical .
2	Describe the oxidative stress and its damages on biomolecules
3	Learn the oxidative stress induced by metals.
4	Classify the antioxidants and explain the mechanism of antioxidants.
5	Know the techniques using for detection of oxidant and antioxidant parameters.
6	Understant the mechanism of various disease related to oxidative stres.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week	Subject	Description
1	Free radicals, The effects of free radicals on biomolecules, Antioxidant defense system, Techniques using for monitoring of oxidant parameters
2	Techniques using for monitoring of antioxidant parameters
3	Discussion of articles related to disease associated with oxidative stres

Recomended or Required Reading

1. Harper s Illustrated Biochemistry. Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW. McGrawHill Lange, 28 th edition, 2009.
2. Newsholme, EA and Leech, TR. Functional Biochemistry in Health and Disease 2010, WILEY-BLACKWELL, Oxford.
3. Reviews related to topics

Planned Learning Activities and Teaching Methods

The course will be run in an integrated way-winding theory with case discussion and laboratory practicals. The methods of learning will be interactive.

Assessment Methods

Successful / Unsuccessful

Further Notes About Assessment Methods

None

Assessment Criteria

If needed, other assessment methods can be added to the table given below.

Language of Instruction

Turkish

Course Policies and Rules

The student is expected to read the resources before coming to class.

Contact Details for the Lecturer(s)

Assist Prof.Dr. Zahide Çavdar
Phone: 412 2617

Office Hours

Tuesdays 13.00-14.00

Work Placement(s)

None

Workload Calculation

Activities	Number	Time (hours)	Total Work Load (hours)
Lectures	15	2	30
Tutorials	30	2	60
Preparations before/after weekly lectures	15	2	30
Preparing assignments	1	15	15
Preparing presentations	1	20	20
Midterm	1	25	25
Final	1	45	45
TOTAL WORKLOAD (hours)			225

Contribution of Learning Outcomes to Programme Outcomes

PO/LO	PO.1	PO.2	PO.3	PO.4	PO.5	PO.6	PO.7	PO.8	PO.9	PO.10	PO.11	PO.12	PO.13	PO.14
LO.1	5	5	4	3	5	4	3	4	5	3	3	3	3	3
LO.2	5	4	4	3	5	4	3	4	5	3	3	3	3	3
LO.3	5	5	4	3	5	4	3	4	5	3	3	3	3	3
LO.4	5	5	4	3	5	4	3	4	5	3	3	3	3	3
LO.5	5	5	5	5	5	4	3	4	5	3	3	3	3	3
LO.6	5	5	4	3	5	4	3	4	5	3	3	5	5	3

COURSE UNIT TITLE

DEGREE PROGRAMMES

Description of Individual Course Units

Offered By

Level of Course Unit

Course Coordinator

Offered to

Course Objective

Learning Outcomes of the Course Unit

Mode of Delivery

Prerequisites and Co-requisites

Recomended Optional Programme Components

Course Contents

Recomended or Required Reading

Planned Learning Activities and Teaching Methods

Assessment Methods

Further Notes About Assessment Methods

Assessment Criteria

Language of Instruction

Course Policies and Rules

Contact Details for the Lecturer(s)

Office Hours

Work Placement(s)

Workload Calculation

Contribution of Learning Outcomes to Programme Outcomes

CONTACT INFORMATION