COURSE UNIT TITLE

: INTRODUCTION TO PROTEOMICS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MOT 6035 INTRODUCTION TO PROTEOMICS ELECTIVE 1 0 0 3

Offered By

Molecular Medicine

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR GÜL HÜRAY IŞLEKEL

Offered to

Molecular Medicine

Course Objective

The aim of this course is to allow the students to learn about proteome and proteomics that is a global research of proteins. Furthermore to acquire knowledge on different research methods and techniques used in proteomics and relations with diseases.

Learning Outcomes of the Course Unit

1   To know about proteome
2   To learn about proteomics
3   To understand the basic principles of techniques used for proteomics
4   To learn about use in proteomics of mass spectrometry
5   To understand clinic proteomics and relations with diseases.
6   To understand about bioinformatic

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 From genome to proteome
2 General properties of proteins
3 Separation techniques in proteome analysis
4 Separation techniques in proteome analysis
5 Identification techniques in proteome analysis
6 Identification techniques in proteome analysis
7 LC-MS MS in proteome analysis
8 Quantitative LC-MS MS in MRM mode in proteome analysis
9 Quantitative LC-MS MS in MRM mode in proteome analysis
10 Linical proteomics
11 Functional proteomics
12 Functional proteomics
13 Bioinformatics
14 General evaluation
15 FINAL

Recomended or Required Reading

1. Articles on laboratory methods published in SCI or expanded SCI journals.
2. Principles of Proteomics R.M. Twyman, Taylor & Francis 2004
3. Clinical Proteomics; From Diagnosis to Therapy , Jennifer E. Van Eyk, Michael J. Dunn, Wiley 2008
4. Protein Sequencing and Identification Using Tandem Mass Spectrometry Michael Kinter and Nicholas E. Sherman, John Wiley, New York,2000
5. Proteomics: A Cold Spring Harbor Laboratory Course Manual Andrew J. Link, CSH Press,2009

Planned Learning Activities and Teaching Methods

The course will be organised as theoretical courses and rotations in different labs.

Assessment Methods

Successful / Unsuccessful

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

The student is expected to read the resources before coming to class. In addition, he/she is expected to contribute actively to discussion.

Contact Details for the Lecturer(s)

Prof Dr. Hüray Işlekel
Phone: 412 44 08

Office Hours

Tuesday: 12.30-13:30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 5 3 15
Preparations before/after weekly lectures 5 5 25
Preparation for final exam 1 15 15
Preparing assignments 1 5 5
Preparation for midterm exam 1 10 10
Final 1 3 3
Midterm 1 2 2
TOTAL WORKLOAD (hours) 75

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.13455
LO.24554
LO.35544
LO.4335
LO.5445
LO.645

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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