COURSE UNIT TITLE

: BIOSAFETY IN LABORATORY ANIMALS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
LHB 6032 BIOSAFETY IN LABORATORY ANIMALS ELECTIVE 1 0 0 3

Offered By

Laboratory Animal Science

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR MERAL KARAMAN

Offered to

Laboratory Animal Science

Course Objective

By this course, it is aimed to gain the students theoretical information about risks that they may encounter and precautions that they should take generally in all laboratories and especially in animal laboratories; to assimilate basic information about biosafety and occupational safety; and to apply these information in every stage of their studies in the laboratory

Learning Outcomes of the Course Unit

1   To be able to examine the laboratory environment about biological, physical, chemical and radiological risks that they may encounter in experimental animal laboratories.
2   To be able to apply, theoretically gained information about good microbiological techniques (GMT) in every stage of their daily studies.
3   To be able to make risk analysis for experimental animal laboratories, to be able to question the working environment and to be able to detect the necessary precaution within the framework of this analysis
4   To be able to assimilate theoretically gained information about separation and disposal of laboratory wastes
5   To be able to understand his/her rights about occupational health and safety

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 What is laboratory safety Laws and regulations. Classification of laboratories, biosafety risk groups
2 Experimental animal laboratories and biosafety risk groups
3 Good laboratory practices, laboratory protective equipment, biosafety cabinets
4 Biological hazards in laboratory , Biological dangers in animal laboratory, Zoonotic infections, Laboratory animal zoonotic infections
5 Laboratory originated infections, laboratory precautions against biological hazards
6 Physical, chemical and radioactive hazards in laboratory
7 Additional risks for animal laboratories, FELASA recommendations for animal laboratories, Organization of safety in laboratory, handbook of biosafety
8 Definition and methods of sterilization, Definition and methods of disinfection, occupational health and safety (laws and regulations)

Recomended or Required Reading

Main Textbook:
1. World Health Organisation. Laboratory Biosafety Manuel . 2004; 3rd ed. WHO, Geneva.

Supplementary Book(s):
1. Ide T, Laboratuvar hayvanları biliminin temel ilkeleri, Ankara, Medipress Yayıncılık, 2003
2. Guide for the Care and Use of Laboratory Animals Institute of Laboratory Animal Resources Commission on Life Sciences National Research Council National Academy Press Washington, D.C. 1996
3. Disinfection, Sterilization, and Preservation, Editor: Seymour S Block.
4. FELASA recommendations for the accreditation of laboratory animal science education and training, Laboratory Animals 36: 373 - 377, 2002.
5. Başaran A, Deney hayvanları; laboratuvar teknikleri, nisan kitabevi yayınları.
6. Centers for Disease Control and Prevention. BMBL Section V. Vertebrate animal biosafety level criteria, 2007.
7. CDC Primary Contaminment for Biohazards: Selection, Installation and Use of Biological Safety Cabinets. 2nd ed, 2000.
References:
1. Temel laboratuvar güvenliği ve ülkemizdeki duruma genel bakış, Meral Karaman, Derleme, J Clin Anal Med 2011;2(3):130-34.
2. Pike RM. Laboratory-associated infections: incidence, fatalities, causes, and prevention. Annu. Rev. Microbiol 1979; 33: 41 66.
3. Kruse RH, Puckett WH, Rıchardson JH. Biological Safety Cabinetry. Clin Microbiol Rev 1991; 4(2): 207-41.

Materials: Presentations, videos

Planned Learning Activities and Teaching Methods

1. Presentations
2. Topic research, interactive discussion and commenting
3. Homework preparation
4. Evaluation of information

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.40 +ASG * 0.20 + FIN* 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.40 +ASG * 0.20 + RST* 0.40

Further Notes About Assessment Methods

None

Assessment Criteria

- It is evaluated if theoretical presentations and interactive discussions were understood or not by midterm and final exam
- Reaching to new information, synthesis of gained information and explaining clearly is evaluated by homework preparation and presentation

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

meral.karaman@deu.edu.tr, 0 232 412 4651

Office Hours

Work hours

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 8 2 16
Preparations before/after weekly lectures 8 2 16
Preparation for midterm exam 1 8 8
Preparation for final exam 1 10 10
Preparing assignments 1 15 15
Preparing presentations 1 6 6
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 75

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12
LO.154
LO.2545
LO.3455
LO.45455
LO.555

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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