COURSE UNIT TITLE

: BIOCHEMISTRY II

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ELECTIVE

Offered By

Chemistry

Level of Course Unit

First Cycle Programmes (Bachelor's Degree)

Course Coordinator

PROFESSOR DOCTOR RAZIYE ÖZTÜRK ÜREK

Offered to

Chemistry
Chemistry (Evening)

Course Objective

The students will learn carbohydrate, lipid and protein metabolisms, fundamental principles of oxidative phosphorylation and photophosphorylation and mechanisms of metabolic regulation.

Learning Outcomes of the Course Unit

1   Students will be able to describe the ATP and the other high energy compounds and their structures, understand that biological energy changes are driven based on the thermodynamic rules.
2   Students will be able to explain the digestion and absorption of carbohydrates, write synthesis and degredation reactions of glucose which is basic energy component, discuss steps of citrate cycles, explain the importance of storage carbohydrates (glycogen and starch) for organisms and write their synthesis and degredation reactions, explain metabolic importance of pentose phosphate pathway and write its reactions
3   Students will be able to explain the structures of complexes that play in electron transfers and know their relationships with other pathways and explain ATP synthesis which is the last step of oxidative phosphorylation, explain structures which play in electron transfer in the photophosphorylation that is occurred in photosynthetic organisms and the role of light in this process and ATP synthesis.
4   Students will be able to write synthesis and degradation reactions of fatty acids, discuss formation of keton bodies and write synthesis steps of cholesterol.
5   Students will be able to examine the degredation steps of amino acids (removal of nitrogen carbondioxide, degradation of C skeleton), discuss urea cycle, explain the importance of nitrogen cycle and write synthesis of amino acids.
6   Students will able to explain the importance of metabolic regulation and discuss regulation mechanisms.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to energy metabolism
2 Glycolysis and glyconeogenesis
3 Oxidative decarboxylation and citrate/glyoxylate cycle
4 Synthesis and degradation of glycogen
5 Pentose phosphate pathway and metabolism of other hexoses
6 Oxidative phosphorylation
7 Photophosphorylation
8 Midterm
9 Synthesis and degradation of fatty acids
10 Formation of keton bodies and cholesterol synthesis
11 Aminoacid degradation: removal of N and CO2; degradation of C skeleton
12 Urea cycle
13 Nitrogen cycle and amino acid synthesis
14 Metabolic regulation

Recomended or Required Reading

1. D.L. Nelson, M.M. Cox, Lehninger Principles of Biochemistry, W.H. Freeman.2005.
2. J.M. Berg, J.L.Tymoczko, L.Stryer, Biochemistry, 5th edition,W.H. Freeman and Company, 2002.
3. D. Voet, J.G. Voet, Biochemistry, Wiley, Third Edition, 2004.
4. R. Boyer, Concepts in Biochemistry, Wiley, Third Edition, 2006.

Planned Learning Activities and Teaching Methods

Presentation
Questions and answers
Homework
Application

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.40 + ASG * 0.20 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.40 + ASG * 0.20 + RST * 0.40


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

The learning of fundamental concepts given in the lectures, associating of concepts, constracting relationship between cause and effect, interpreting on the questions through current knowledge, and evaluation of idea production will be carried out by mid terms, final exam, active participation to the lecture, home works. The lecturer informs the student about the assignments and their collection dates within first four weeks. The assignments with signatures are collected within the last two weeks.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

raziye.urek@deu.edu.tr

Office Hours

It will be announced according to the programme.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 13 4 52
Tutorials 13 2 26
Preparations before/after weekly lectures 13 4 52
Preparation for midterm exam 1 20 20
Preparation for final exam 1 30 30
Preparing assignments 2 8 16
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 200

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14PO.15PO.16PO.17
LO.1545455
LO.21115555
LO.31445555
LO.431445555
LO.511445555
LO.621445555