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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS OBY 3011 MOLECULAR BIOLOGY COMPULSORY 4 0 0 5

Offered By

Biology Teacher Education

Level of Course Unit

First Cycle Programmes (Bachelor's Degree)

Course Coordinator

Offered to

Biology Teacher Education

Course Objective

To understand of the nature and organisation of the genetic material, and the mechanisms of replication, transmission and change, and the processes controlling its expression.

Learning Outcomes of the Course Unit

1   describe the structure of nucleic acids 2   explain gene organisation and expression 3   explain mechanisms of replication, transcription and translation

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 A brief history of molecular biology 2 Structure and functions of nucleic acids 3 30 nm chromatin fiber, histons and structure of nucleosome 4 DNA packaging (chromosomes) 5 Prokaryotic and Eukaryotic replication 6 Structure of DNA polymerase holoenzyme 7 The oriC replication model 8 Mid-term exam 9 Structure of prokaryotic RNA polymerase 10 Transcription of Prokaryotic genes: Initiation, elongation and termination 11 Transcription of Eukaryotic genes: RNA polymerase I, II and III 12 Posttranscriptional modifications 13 Translation (Protein synthesis): Initiation, elongation and termination. 14 Enzymes of restriction endonuclease and genetic engineering 15 Final exam

Recomended or Required Reading

Lehninger, A. L.; Nelson, D. L.; Cox, M. M. (2000). Pirinciples of Biochemistry, 3rd ed. New York, Worth Publishers Inc. Dingermann, Th., Steinhilber, D., Folkers G. (2004) Molecular Biology in Medicinal Chemistry, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Planned Learning Activities and Teaching Methods

Discussion, group work, question-answer.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 VZ Ara Sınav 2 FN Yarıyılsonu Sınavı 3 BNS BNS VZ * 0.40 + FN * 0.60 4 BUT Bütünleme Notu 5 BBN Bütünleme Sonu Başarı Notu VZ * 0.40 + BUT * 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

To be announced.

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Theoretical 13 4 52 Pre Class Self Study 14 2 28 Midterm Preparation 1 10 10 Final Preparation 1 10 10 Research Presentation 2 10 20 Final Exam 1 1 1 Midterm Exam 1 1 1 TOTAL WORKLOAD (hours) 122

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 PO.11 PO.12 PO.13 PO.14 LO.1 4 2 4 3 3 LO.2 4 2 4 3 3 LO.3 4 2 4 3 3