COURSE UNIT TITLE

: INTRODUCTION TO BIOCHEMISTRY

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
OKM 3120 INTRODUCTION TO BIOCHEMISTRY COMPULSORY 2 0 0 4

Offered By

Chemistry Teacher Education

Level of Course Unit

First Cycle Programmes (Bachelor's Degree)

Course Coordinator

ASSOCIATE PROFESSOR ŞENOL ALPAT

Offered to

Chemistry Teacher Education

Course Objective

Being aware of the importance of function and basic biochemical concepts, can establish a relationship to Other Disciplines

Learning Outcomes of the Course Unit

1   Possess a general knowledge of the major types of biomolecules, including small, large and supermolecular components found in living cells.
2   Understand the structure and function of the basic biomolecules in living cells and the roles in cellular and organismal function.
3   Recognize the different types of biomolecules and know their essential characteristics and molecular stability that make them indispensable for life
4   Recognize the value of importance of biochemistry in everyday life in the 21th century
5   Be exposed to the frontiers of biochemical work and recognize the importance of cross disciplinary approaches to biochemical problems.
6   Communicate in both written and oral forms and be able to work in groups both in class room and in the laboratory environment.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Scope of Biochemistry, the role of water in Biological processes
2 Amino acids; structure/stereochemistry of amino acids, Classification and properties of side chains of amino acids, essential amino acids, ionization of amino acids and isoelectric point, amino acid reactions
3 Peptides; classification and nomenclature, peptide bond and structure, stability and formation of peptide bond, conformations, rotations, peptides as polyampholytes, Basics of peptide structure analysis; N-, C- terminal analysis
4 Proteins; Functional and structural classification, Organization of protein structure, Primary structure: nature of protein sequences, Secondary structure: helices and plated sheets, stability, ß-turn, random coil, characteristics
5 Tertiary structure; Factors effecting tertiary structure formation, Thermodynamics of protein folding, Charperones, Denaturation Quaternary structures
6 Preview of protein isolation and purification
7 Protein purification techniques
8 Midterm exam
9 Enzymes; Terminology, classification and properties, principles of catalysis and enzyme inhibition, regulation of enzyme activity
10 Carbohydrates, classification, structure
11 Redox properties of carbohydrates, and the reactions
12 Lipids, classification, properties, structure
13 Nucleic acids; The nature of nucleic acids, Primary, secondary and tertiary structure of nucleic acids; base pairing
14 Double helices, circular DNA and super coiling, Denaturation / renaturation of DNA, DNA melting point, Principles of nucleic acid sequencing
15 Final Exam

Recomended or Required Reading

Main source: Lehninger Principles of Biochemistry , 5 th Edn. Palgrave Macmillan, (2008)
Supporting Resources: Voet D., Fundamentals of Biochemistry: Life at the molecular Level.(2008), Horton R., Principles of Biochemistry, Prentis Hall (2005), Boyer R. Interactive Concepts in Biochemistry 2/e, Wiley (2008)

Planned Learning Activities and Teaching Methods

Brainstorming, cooperative learning, problem-based learning, interactive learning, presentation

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 VZ Arasınav
2 DTK Diğer Etkinlik
3 FN Yarıyılsonu Sınavı
4 BNS BNS VZ * 0.30 + DTK * 0.10 + FN * 0.60
5 BUT Bütünleme Notu
6 BBN Bütünleme Sonu Başarı Notu VZ * 0.30 + DTK * 0.10 + BUT * 0.60


Further Notes About Assessment Methods

None

Assessment Criteria

30% midterm exam+10%assignment+60% final exam

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

senol.alpat@deu.edu.tr

Office Hours

Monday 10.00-12.00 am

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 13 2 26
Preparations before/after weekly lectures 13 1 13
Preparation for midterm exam 1 15 15
Preparation for final exam 1 20 20
Preparing assignments 1 10 10
Preparing presentations 1 10 10
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 98

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14PO.15PO.16PO.17PO.18PO.19
LO.1553553533
LO.25555
LO.353354
LO.44555
LO.55555
LO.65545