COURSE UNIT TITLE

: PRODUCTION OF SECONDARY METABOLITES

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BYT 6002 PRODUCTION OF SECONDARY METABOLITES ELECTIVE 3 0 0 9

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR LEMAN TARHAN

Offered to

Ph.D. in Biotechnology
BIOTECHNOLOGY

Course Objective

It is aimed to examine by considering the strategies, metabolic pathways, regulations, production and application of plant and microbial based seconder metabolite at the industrial scale production of seconder metabolites.

Learning Outcomes of the Course Unit

1   Students will be able to generate ideas and discuss for significance of secondary metabolites, production of secondary metabolites
2   Students will be able to generate ideas and discuss for significance of metabolic pathways and regulations related with secondary metabolites.
3   Students will be able to have knowledge about production of plant based metabolite and examine.
4   Students will be able to have knowledge about production of microbial secondary metabolites and examine.
5   Students will be able to examine about economical production of secondary metabolites.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Overview on Secondary Metabolism 1.1. The Importance of Secondary Metabolites as Drug 1.2. Regulation of Secondary Metabolite Production 1.3. Secondary Metabolite Pathways
2 The Secondary Metabolites with the featured of Antibacterial, Antifungal and Antiviral Specialty
3 Plant-Based Secondary Metabolites 3.1. Recent Medical Applications of plant secondary metabolites
4 Plant-Based Secondary Metabolites 4.1. Secondary Metabolite Production with Plant Cell Cultures
5 Antibiotics 5.1. Regulation of Bacterial Antibiotic Production
6 Antibiotics 6.1. ß-lactam, Peptide, Lantibiyotic, Glycopeptide, Polyketide Antibiotics
7 Phenols, Polyphenols and Tannins
8 MIDTERM EXAM
9 Sulfur-Containing Compounds
10 Terpenes and Alkaloids
11 Acetylene and Psoralens
12 Flavonoids
13 Antitumor Agents 13.1. Classic Anticancer Drugs 13.2. Non-Classical Approaches to Antitumor Drugs
14 Homework and Presentations

Recomended or Required Reading

Textbook(s): H.-J. Rehm, G. Reed, Biotechnology: Products of Secondary Metabolism, Volume 7, Second Edition, Wiley Company, 2008.
Supplementary Book(s): M. Wink, Functions and Biotechnology of Plant Secondary Metabolites, Second Edition, Blackwell Publishing Ltd, 2010.
B. Shen, Biosynthesis of Aromatic Polyketides, Topics in Current Chemistry, Vol. 209, Springer-Verlag Berlin Heidelberg, 2000.

Planned Learning Activities and Teaching Methods

1. Presentation
2. Question-answer technique
3. Homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 PRS PRESENTATION
4 FIN FINAL EXAM
5 FCG FINAL COURSE GRADE MTE* 0.30 + ASG * 0.20 + PRS * 0.10 + FIN * 0.40
6 RST RESIT
7 FCGR FINAL COURSE GRADE (RESIT) MTE* 0.30 + ASG * 0.20 + PRS * 0.10 + RST * 0.40


Further Notes About Assessment Methods

None

Assessment Criteria

Meaningful learning of the basic concepts given in presentations, association of concepts with each other, establishing the cause-result relationships and making comments by using the information available for problems and evaluating idea generation are carried out with mid-term and final exams, homework and presentations.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Dokuz Eylul University, Faculty of Science, Department of Chemistry
leman.tarhan@deu.edu.tr

Office Hours

Wednesday 13.30 - 15.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 13 3 39
Preparations before/after weekly lectures 13 3 39
Preparation for midterm exam 1 40 40
Preparations before/after weekly lectures 1 50 50
Preparing Homework and Presentations 1 45 45
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 217

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6
LO.1453543
LO.2454544
LO.3543444
LO.4544453
LO.5454543

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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