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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS BYT 5025 BASIC BIOCHEMICAL CONCEPTS IN BIOTECHNOLOGY COMPULSORY 3 0 0 8

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR LEMAN TARHAN

Offered to

BIOTECHNOLOGY

Course Objective

In the context of this course, the students will learn fundamental principles of biochemistry, structures, functions and metabolisms of protein, carbohydrate, lipid and nucleic acids as well as regulations of these metabolisms.

Learning Outcomes of the Course Unit

1   Explain the importance of the water and chemical reactions occurred in the biological systems, 2   Describe the DNA and RNA structures and functions, 3   Explain the structures and general properties of the amino acids, carbohydrates and lipids, 4   Explain the enzymes , as biological catalysts, function and catalyst mechanisms, kinetics and explain the importance of coenzymes which are necessary for catalytic activities of enzymes, 5   Write synthesis and degradation reactions of carbohydrates, fatty acids and explain the functions of enzymes that catalysed these reactions. 6   Discuss conversion of pruvate that is degradation product of glucose into acetyl-CoA and steps of further degradation of acetyl CoA for energy production. 7   Explain the differences of glyoxylate cycle from citrate cycle and its metabolic importance. 8   Explain the structures of complexes that play in electron transfers and know their relationships with other pathways and explain ATP synthesis.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Biochemistry: From Atoms to Molecules to Cells and Water 2 Amino Acids, Peptides and Proteins, 3 Protein Architecture and Biological Function 4 Enzymes and Coenzymes 5 Carbohydrates and Lipids: Structures and Biological Functions 6 DNA and RNA:Structure and Functions 7 Translation of RNA and Recombinant DNA Technology 8 Midterm exam 9 Metabolism, Basic Concepts of Bioenergetics and Metabolism of Carbohydrates 10 Citric Acid Cycle, Glyoxylate Cycle and Pentose Phosphate Pathway 11 ATP Formation by Electron-Transport Chains 12 Metabolism of Fatty Acids 13 Metabolism of Amino acids and Other Nitrogenous Compounds, Integration, Specialization, and Hormonal Control of Metabolism 14 Student s Presentation

Recomended or Required Reading

Textbook(s): Boyer R. Concepts in Biochemistry Wiley Inc., 2006. Supplementary Book(s): Pratt C.W., Cornely K. Essential Biochemistry Wiley Inc., 2011.

Planned Learning Activities and Teaching Methods

1. Presentation 2. Interactive narrative 3. Question-answer technique 4. Homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 ASG ASSIGNMENT 2 MTE MIDTERM EXAM 3 FIN FINAL EXAM 4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40 5 RST RESIT 6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof.Dr.Raziye Ozturk Urek DEU Sci Fac. Chemistry Dept. 35160 Buca-Izmir Tel: 0 232 3018689 e-mail: raziye.urek@deu.edu.tr

Office Hours

Wednesday 16:00-17:00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 13 3 39 Preparations before/after weekly lectures 13 5 65 Preparation for midterm exam 1 30 30 Preparation for final exam 1 30 30 Preparing presentations 1 21 21 Midterm 1 2 2 Final 1 2 2 TOTAL WORKLOAD (hours) 189

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 LO.1 3 4 LO.2 4 LO.3 3 LO.4 4 3 LO.5 LO.6 3 LO.7 LO.8 3