COURSE UNIT TITLE

: BIOHEAT TRANSFER

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BMT 5037 BIOHEAT TRANSFER ELECTIVE 3 0 0 8

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR MUSTAFA SERHAN KÜÇÜKA

Offered to

Industrial Ph.D. Program In Advanced Biomedical Technologies
Biomedical Tehnologies (English)

Course Objective

The student will be able to derive the energy balance for the living tissue and gain the ability of modeling of heat effects for thermal therapy methods such as magnetic field and laser heating treatments, etc. They will analyze basic bio-heat problems using computer aided modeling tools.

Learning Outcomes of the Course Unit

1   Stating energy balance in a control volume
2   Stating energy balance for a tissue using Pennes model
3   Obtaining analytical solution of bio-heat problems in 1D
4   Stating transient problems in bio-heat
5   Obtaining some basic solutions of bio heat problems using simulation models

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Basic principles of heat transfer - Fourier s law of heat conduction (diffusion) - Newton s cooling law - A basic introduction to heat radiation
2 Derivation of general energy equation on a differential volume
3 Conductive heat transfer equation - Boundary conditions - Homogenous and non-homogenous equations
4 Basic descriptions of bio-heat transfer and Pennes model - Basic descriptions of bio-heat transfer - Pennes model - Modifications of Pennes Model, Wulff s, Klinger s and others models.
5 One dimensional solutions of Pennes equation - Sample problem-1: Solution of the heat transfer problem in 1D Cartesian coordinates for the tissue with blood perfusion - Sample problem-2: Solution of the heat transfer problem in 1D cylindrical coordinates for the tissue with blood perfusion.
6 Transient problems with lumped analysis - Energy balance for lumped analysis - Sample problem: Tissue cooling in a medium with variable temperature
7 Transient problems in 1D coordinates - 1-D Transient problems using separation of variables - 1-D Transient problems with heat generation
8 Transient problems in semi-infinite media(1) Similarity solution for 1-D transient conduction in semi-infinite media
9 Transient problems in semi-infinite media(2) Integral energy approach for 1-D transient conduction in semi-infinite media
10 An introduction to computer modeling of bio-heat problems(1) Basic principles to define a model for computer aided simulation
11 An introduction to computer modeling of bio-heat problems(2) Bio-heat modeling guidelines
12 Sample problem: 2D axisymmetric tumor laser irradiation model (1)
13 Sample problem: 2D axisymmetric tumor laser irradiation model (2)
14 Discussion about the assignments

Recomended or Required Reading

Textbook(s): : Poulikakos, D., Conduction Heat Transfer, Prentice Hall, 1994
Supplementary Book(s):
- Valvano, J. W., BioHeat Transfer, Wiley Online Library, DOI: 10.1002/0471732877.emd015, 2006.
- Zolfaghari A., Maerefat M., Chapter 3.-BioHeat Transfer, Developments in Heat Transfer, ed.S. Bernardes, InTech, 2011.
- Pryor R. W., Multi-Physics Modeling Using COMSOL, Bartlett Publishers, 2011

Planned Learning Activities and Teaching Methods

Instructor will assign several problems related to bio-heat transfer during the semester. The students will be asked to solve the given problem analytically and/or numerically. Students are required to work individually.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 PRS PRESENTATION
3 FCG FINAL COURSE GRADE ASG * 0.50 + PRS * 0.50


Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

The course is taught in a lecture, class presentation and discussion format. All students are expected to attend the lectures.

Contact Details for the Lecturer(s)


serhan.kucuka@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 4 56
Preparing assignments 6 12 72
Preparing presentations 1 30 30
TOTAL WORKLOAD (hours) 200

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.14544
LO.24544
LO.34544
LO.44544
LO.545445

CONTACT INFORMATION
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Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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