Dokuz Eylül University Information Package / Courses Catalog

Description of Individual Course Units

Course Unit Code	Course Unit Title	Type Of Course	D	U	L	ECTS
KIM 6110	REGULATION OF ENZYME ACTIVITY	ELECTIVE	3	0	0	7

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR LEMAN TARHAN

Offered to

M.Sc. in Biochemistry
Chemistry
Ph.D in Biochemistry

Course Objective

Enzyme activity regulation types which are of importance in terms of balance in metabolic systems occuring in cell, their mechanisms and importance will be discussed by correlating all biochemical cycles in animal, plant and bacteria samples.

Learning Outcomes of the Course Unit

1	Have a knowledge as to metabolic control theory and analysis of enzyme activity,
2	Examine scheduling in mechanisms and control steps by explaining enzyme activity regulation types,
3	Explain regulation with ligand binding and reversible covalent modification in enzyme activity,
4	Relate among and discuss intracellular signal transduction systems, signal donors and transmitters and exchangers,
5	Give examples to application areas in diseases treatment of activators and inhibitors in enzyme activity regulation by discussing their importance.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week	Subject	Description
1	Enzymes, Isoenzymes and Their Metabolic Importance
2	Metabolic Control Theory and Analysis
3	Types of Enzyme Activity Regulation, Timing and Control in Mechanisms-I
4	Types of Enzyme Activity Regulation, Timing and Control in Mechanisms-II
5	Regulation in Enzyme Activity by Ligand Binding
6	Regulation by Reversible Covalent Modification in Animal, Plant and Bacteria
7	Intracellular Signal Transduction System, Signal Transmitters, Transducers and Exchangers-I
8	Midterm Exam
9	Intracellular Signal Transduction System, Signal Transmitters, Transducers and Exchangers-II
10	Enzyme Regulation in Plants
11	Regulation in Enzyme Expressing Genes
12	Enzyme Cascades
13	Importance of Activators and Inhibitors in Regulation of Enzyme Activity and Their Usages in Treatment of Diseases
14	Presentations

Recomended or Required Reading

Textbook(s): Ottaway J. H., Regulation of Enzyme Activity, Oxford University Press, USA; NULL edition, 1988.
Supplementary Book(s): Krauss G., Biochemistry of Signal Transduction and Regulation, Copyright © 2001 Wiley-VCH Verlag GmbH.

Planned Learning Activities and Teaching Methods

1. Presentation
2. Interactive narrative
3. Question-answer technique
4. Homework

Assessment Methods

SORTING NUMBER	SHORT CODE	LONG CODE	FORMULA
1	MTE	MIDTERM EXAM
2	ASG	ASSIGNMENT
3	PAR	PARTICIPATION
4	FIN	FINAL EXAM
5	FCG	FINAL COURSE GRADE
6	RST	RESIT
7	FCGR	FINAL COURSE GRADE (RESIT)

Further Notes About Assessment Methods

None

Assessment Criteria

Meaningful learning of the basic concepts given in presentations, association of concepts with each other, establishing the cause-result relationships and making comments by using the information available for problems and evaluating idea generation are carried out with mid-term and final exams, active participation to the lecture, homework.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

leman.tarhan@deu.edu.tr

Office Hours

Wednesday 13.30 15.30

Work Placement(s)

None

Workload Calculation

Activities	Number	Time (hours)	Total Work Load (hours)
Lectures	13	3	39
Preparations before/after weekly lectures	13	3	39
Preparation for midterm exam	1	10	10
Preparation for final exam	1	20	20
Preparing assignments	2	15	30
Preparing presentations	2	15	30
Final	1	2	2
Midterm	1	2	2
TOTAL WORKLOAD (hours)			172

Contribution of Learning Outcomes to Programme Outcomes

PO/LO	PO.1	PO.2	PO.3	PO.4	PO.6	PO.8	PO.9	PO.10	PO.11
LO.1	5	5	5	5	5	5	5
LO.2	5	5	5	5	5	5	5		5
LO.3	5	5	5	5	5	5	5
LO.4	5	5	5	5	5	5	5
LO.5		5	5	5	5	5	5	5	5

COURSE UNIT TITLE

DEGREE PROGRAMMES

Description of Individual Course Units

Offered By

Level of Course Unit

Course Coordinator

Offered to

Course Objective

Learning Outcomes of the Course Unit

Mode of Delivery

Prerequisites and Co-requisites

Recomended Optional Programme Components

Course Contents

Recomended or Required Reading

Planned Learning Activities and Teaching Methods

Assessment Methods

Further Notes About Assessment Methods

Assessment Criteria

Language of Instruction

Course Policies and Rules

Contact Details for the Lecturer(s)

Office Hours

Work Placement(s)

Workload Calculation

Contribution of Learning Outcomes to Programme Outcomes

CONTACT INFORMATION