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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS ERS 5005 INTRODUCTION TO CELL ELECTIVE 3 0 0 6

Offered By

Medical Biology and Genetics

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR OĞUZ ALTUNGÖZ

Offered to

Medical Biology and Genetics

Course Objective

To become familiar with functional and structural aspects of the cell.

Learning Outcomes of the Course Unit

1   To conceptualize molecular and cellular aspects of life 2   To become familiar with genetic and epigenetic mechanisms at the cellular level 3   To learn structure and function of subcellular compartments of mammalian cells 4   To understand regulation of mammalian cell cycle 5   To learn abnormal functioninig of cell in relation to human diseases 6   To became familiar with basic mechanisms of cell communication

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Introduction 2 Why Water is so Important Solubility, ionization, polarity, pH, pK etc., Chemical Bonds and Main Reactions 3 The Composition of Living Matter: Biomolecules 4 Structure of Nucleic Asids (DNA & RNA) and Replication of DNA 5 Transcription and Translation, Post-transcriptional and Post-translational Modifications Prokaryotic and Eukaryotic Cell Structure 6 Endoplasmic Reticulum, Golgi and Intracellular Traffic 7 Bioenergetics, Mitochondria,Introduction to Metabolism 8 Cell skeleton, Intracellular movements 9 Structure of Nucleus; Nuclear Envelope, Pores, Definition of Genes and Genomes; Chromatin 10 Transport Through Membranes; Molecules, Ions 11 Cell Cycle Regulation and Apoptosis 12 Cell Communication

Recomended or Required Reading

Cell Biology. Pollard & Earnshaw, SAUNDERS Elsevier, 2008 The Cell: A Molecular Approach. Geoffrey M. Cooper. 6th ed. 2013. Molecular Biology of the Cell. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. 6th ed. 2014 6th ed. Lehninger Principles of Biochemistry. David L. Nelson, Michael M.Cox, 5th ed., Worth Publishers, New York, 2008.

Planned Learning Activities and Teaching Methods

Assay reading, problem solving and take home assignments.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 PRF PERFORMANCE 2 FIN FINAL EXAM 3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60 4 RST RESIT 5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

Lectures are carried out interactively.

Contact Details for the Lecturer(s)

Oğuz Altungöz, PhD Dokuz Eylül Medical School Medical Biology and Genetics oguz.altungoz@deu.edu.tr

Office Hours

Two hours ina week

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Student Presentations 1 1 1 Lectures 15 3 45 Preparation for final exam 15 2 30 Preparation for midterm exam 7 6 42 Reading 15 2 30 Final 1 2 2 Midterm 1 3 3 TOTAL WORKLOAD (hours) 153

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 LO.1 4 2 2 2 2 2 LO.2 2 4 2 2 2 2 LO.3 2 3 2 2 2 LO.4 2 2 2 2 2 LO.5 2 2 2 2 2 LO.6 4 2 2 2 3