COURSE UNIT TITLE

: MOLECULAR GENETICS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TBG 5030 MOLECULAR GENETICS ELECTIVE 3 0 0 6

Offered By

Medical Biology and Genetics

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR HAKKI OGÜN SERCAN

Offered to

Biochemistry
Basic Oncology
Molecular Medicine
Medical Biology and Genetics
Pharmacology
Toxicology

Course Objective

Objectives of this course are:
*To acquire basic knowledge on the concepts and processes that form the foundations of molecular biology
*To gain an understanding of the biology of living cells

Learning Outcomes of the Course Unit

1   Outlines the structure and biochemical features of nucleic acids.
2   Recounts the basic knowledge on replication, transcription, post-transcriptional modifications and translation in eukaryotes and prokaryotes
3   Describes the processes that transforms a polypeptide chain in to a functional protein (post-translational modifications, protein folding, protein targeting, protein degradation ect.)
4   Knows and repeats the genetic regulation mechanisms in prokaryotes and eukaryotes.
5   Outlines genetic recombination mechanisms.
6   Describes the cell skeleton and its role in cell motility & mobility
7   Explains features of the cell surface
8   Describes the basic concept of the cell cycle and its regulation

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction
2 Nucleic acid structure & genetic data
3 DNA Replication
4 Transcription: RNA synthesis
5 Post-transcriptional modifications in prokaryotes & eukaryotes
6 Translation: Protein synthesis and structure
7 Post-translational modifications and protein targetting
8 MID-TERM EXAM
9 Genetic regulation in in prokaryotes & eukaryotes I
10 Genetic regulation in in prokaryotes & eukaryotes II
11 Genetic recombination
12 Cell cycle & its control
13 The cell skeleton & mobility
14 The cell skeleton & mobility
15 General review of the course
16 FINAL EXAM

Recomended or Required Reading

Textbook(s):
1. Hücre, Moleküler Yaklaşım, (The Cell, A Molecular Approach 2nd edition Geoffey M. Cooper, Robert E. Hausman.) Çeviri Editörleri: Meral Sakızlı, Neşe Atabey. Izmir Tıp Kitabevi, ISBN: 9944-5148-0-2, Ankara 2006 .
2. Hücrenin Moleküler Biyolojisi, (Molecular Biology of the Cell,4th Edition. Ed. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. Garland Publishers) Çeviri Editörleri: Nur Buyru, Nejat Dalay, Meral Özgüç, Mehmet Öztürk, Meral Sakızlı, ISBN: 978-9944-252-22-5, TÜBA ders kitapları, 2008
Supplementary Book(s):
References:
Materials:

Planned Learning Activities and Teaching Methods

Lectures: Basic theoretical concepts will be explained during lectures
Homework: Students are expected to hand in 4 written reports on topics that are given by the course coordinator.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE MTE * 0.40 + FIN* 0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE MTE * 0.40 + RST* 0.60


Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Tel: 232 412 4623 E-posta: ogun.sercan@deu.edu.tr

Office Hours

Wednesday s 15:30-17:00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 3 45
Preparation before/after weekly lectures 15 3 45
Preparation for midterm exam 1 6 6
Preparation for final exam 1 10 10
Preparing individual assignments 6 6 36
Final 1 3 3
Midterm 1 3 3
TOTAL WORKLOAD (hours) 148

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.111441444
LO.211441444
LO.311441444
LO.411441444
LO.511441444
LO.611441444
LO.711441444
LO.811441444

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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