COURSE UNIT TITLE

: CANCER RESEARCH LABORATORY II

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 5046 CANCER RESEARCH LABORATORY II ELECTIVE 2 2 0 4

Offered By

Basic Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR YASEMIN BASKIN

Offered to

Basic Oncology

Course Objective

The aim of this course the acquisition of basic knowledge about cancer research laboratory, introduce new technologies and related laboratory methods and thus their thesis and research projects associated with analytical studies will continue.

Learning Outcomes of the Course Unit

1   Capable of outlined in general laboratory rules and working instructions can Express.
2   . Capable of outlined in the analysis methods of types of PCR, microarrays, hybridization, flow cytometry, cytotoxicity, apoptosis can express.
3   Be able to adapt the methods of laboratory analysis of the underlying
4   Be able to apply the basic methods of sample preparation
5   Be able to apply the methods of RCR, RT PCR, cytotoxicity, apoptosis.
6   Be able to research and ınquire about the work of cancer cell culture.
7   Be able to critically evaluates the published literature in the field of cancer research and adapt their own applications

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Principles of advanced techniques of analysis
2 Molecular techniques of Cancer Genetics, genetic markers of cancer,
3 DNA and RNA analysis in cancer research
4 Cancer-specific Polymerase Chain Reaction (PCR) applications and real-time PCR applications
5 Cancer-specific mutation detection techniques,
6 Blotting techniques (Western, Southern, Northern) in cancer research
7 DNA microarrays in cancer,
8 specific techniques of cancer cell pathways (cell cycle, apoptosis, sitotoksiiste)
9 Cancer-specific immunohistochemical techniques,
10 Flow cytometer in cancer,
11 Comparative Genomic Hybridization of Cancer,
12 Allele specific oligonucleotide hybridization in cancer, in situ hybridization
13 Cancer-specific Protein Analysis,
14 Recombinant DNA technology overview,
15 Recombinant DNA technology overview,

Recomended or Required Reading

Textbook(s): Prof.Dr. Ahmet Münir KINAY,Prof.Dr. Ahmet Uğur YILMAZ,Prof.Dr. Hülya ELLIDOKUZ,Prof.Dr.Safiye AKTAŞ,Doç.Dr. Zekiye Sultan ALTUN, Yrd.Doç.Dr. Yasemin BASKIN,MSc. Pınar,Erçetin,YL Öğr Gizem Çalıbaşı,"Temel Onkolojide Kullanılan Araştırma Yöntemleri", Dokuz Eylül Üniversitesi Matbaası, Izmir,978-975-441-330-4,(2011) ,El Kitabı(Handbook)
Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition; The Biology of Cancer Robert A. Weinberg, Gariand Science 2007; Moleküler Biyoloji, Editör: Ahmet Yıldırım Nobel Yayın Dağıtım; Ankara, 2010,
References:
Materials: Pubmed

Planned Learning Activities and Teaching Methods

Theoretical and applied Lectures, the topics in-class activities (presentations and assignments) to consolidate and discussion, laboratory applications, and application assignments

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 LAB LABORATORY
4 FIN FINAL EXAM
5 FCGR FINAL COURSE GRADE MTE * 0.20 + ASG * 0.10 + LAB* 0.20 + FIN*0.50
6 RST RESIT
7 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.20 + ASG * 0.10 + LAB* 0.20 + RST*0.50


Further Notes About Assessment Methods

None

Assessment Criteria

1. The learner will clearly define outlined LO1,LO2, LO3 which will evaluate with presentations prepared by themselves, homework and their laboratory applications .
2. The learner will clearly apply analysis methods of cancer laboratory practices.
3. The learner will assignments LO4, LO5, making the presentation and homework.
4. The learner will recognize LO1, LO2, LO3, LO7; will evaluate with homework, prepared presentations by themselves and exam.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

yasemin.baskin@deu.edu.tr 0 232 4125890/5801

Office Hours

Monday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Tutorials 15 1 15
Preparation for midterm exam 1 15 15
Preparation for final exam 1 18 18
Preparing assignments 1 10 10
Preparing presentations 1 10 10
Final 1 1 1
Midterm 1 1 1
TOTAL WORKLOAD (hours) 100

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.15555
LO.25555
LO.35555
LO.455555
LO.5555555
LO.655555555
LO.755555

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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