COURSE UNIT TITLE

: STUDIES IN THE BEHAVIORAL NEUROSCIENCE LABORATORY ANIMALS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
LHB 5010 STUDIES IN THE BEHAVIORAL NEUROSCIENCE LABORATORY ANIMALS ELECTIVE 2 2 0 8

Offered By

Laboratory Animal Science

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR OSMAN YILMAZ

Offered to

Laboratory Animal Science

Course Objective

It is aimed to teach behavior mechanism in laboratory animals, normal and pathological behaviors. It is aimed to enable researchers and students to use these knowledge and skills in their own animal behavior studies.

Learning Outcomes of the Course Unit

1   LO 1. To be able to understand behavior mecanism of experimental animal
2   LO 2. To be able to understand basic and pathologic behaviors of laboratory animals
3   LO 3. Should learn behavior tests of experimental animals.
4   LO 3. Should learn behavior tests of experimental animals.
5   LO 4. Should learn how to analyze behavior tests of experimental animals
6   LO 5. To be able to evaluate stress and discomfort
7   LO 6. Researchers who use experimental animals should have basic knowledge and skills should be able to put into practice what he/she learned in order to carry out their experiment

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 T: Origin, etiology, historical development of normal behavior in laboratory animals, Neurobiology of behavior (CNS, ANS, endocrine, hormones, fremones) Welfare of laboratory animals P: Basic manipulations in Experimental animals
2 T: Behavioral disorders in laboratory animals Symptoms of behavioral disorders (stress, aggression, anxiety ) Species specific behavioral disorders P: Observation of behavior of laboratory animals inside the cage
3 T: The characteristics of behavior studies in laboratory animals Advantages, disadvantages, strengths and limitations of tests Experimental design P: Observation of behavior of laboratory animals inside the cage
4 T: The characteristics of behavior studies in laboratory animals Design of the laboratory Ethical circumstances P: Practice of behavioral test
5 T: Methods used for neurological and physiological evaluation of laboratory animals. Methods used for evaluating locomotor activity, locomotor activity, coordination P: Practice of behavioral test
6 T: Methods used for neurological and physiological evaluation of laboratory animals. Methods used for evaluating sensory skills P: Practice of behavioral test
7 T: Methods used for neurological and physiological evaluation of laboratory animals. Methods used for evaluating the social interaction skills P: Practice of behavioral test
8 MID-TERM EXAM
9 T: Methods used for neurological and physiological evaluation of laboratory animals. Methods used for evaluating learning and cognitive skills. P: Practice of behavioral test
10 T: Behavioral analysis methods for animal models of neurological and physiological diseases (preclinical models of diseases) Preclinical models of cerebral hypoxia and ischemia and behavioral tests P: Practice of behavioral test
11 T: Behavioral analysis methods for animal models of neurological and physiological diseases (preclinical models of diseases) Preclinical models of degenerative diseases and behavioral tests P: Practice of behavioral test
12 T: Behavioral analysis methods for animal models of neurological and physiological diseases (preclinical models of diseases) Preclinical models and behavioral tests of diseases like bipolar disorder, depression, anxiety, schizophrenia P: Practice of behavioral test
13 T: Behavioral analysis methods for animal models of neurological and physiological diseases (preclinical models of diseases) Preclinical models and behavioral tests of drug addiction P: Practice of behavioral test
14 T: Evaluation of data obtained by observation or measurement P: Evaluation by video tracking program Ethovision XT 9.0
15 T: Homework presentations

Recomended or Required Reading

Textbook(s)/References/Materials:
Charles R. Gerfen, Andrew Holmes, David Sibley, Phil Skolnick, Susan Wray; Past Editors: Jacqueline Crawley; Ron McKay; and Michael Rogawski. Current protocols in neuroscience, Online ISBN: 9780471142300; DOI: 10.1002/0471142301
Tayfun Uzbay, Psikofarmakolojinin Temelleri ve Deneysel Araştırma Teknikleri. Ankara, 2004
Tayfun Ide; Laboratuvar hayvanları biliminin temel ilkeleri, Ankara, 2003
R.Barone, C.PAVAUN, p.c. Blın, P.Cuq : Anatomıe DuLapın, Atlas Of Rabbıt Anatomy, Masson c. Editeurs 1973
Sıegfrıed Jung : Grundlagen fürdie Zucht und Haltung der wichtigsten Versuchstiere, Gustov Fıscher Verlag Stutgart 1961.
Patrick F.Sharp. Marie C.La Regina, : The Laboratory Rat, CRC Press London 1998
H.B Waynforth: Experimental and Surgical Technique in the Rat Academıc Press London 1980
James G . Fox, Bennett. J. Cohen, Franklin M. Loew : Laboratory Animal Medicine, Academıc Press, Inc. 1984.

Planned Learning Activities and Teaching Methods

1. Presentations and practices
2. Topic research, interactive discussion and commenting
3. Homework preparation
4. Evaluation of information

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.60 +ASG * 0.10+ FIN* 0.30
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.60 +ASG * 0.10+ RST* 0.30


Further Notes About Assessment Methods

None

Assessment Criteria

- It is evaluated if theoretical presentations and interactive discussions were understood by midterm and final exams
- It is evaluated if reference study, data collection, compilation, ability of synthesizing gained information and explaining it clearly by homework preparation and presentation

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof.Dr.Osman YILMAZ, 0 232 412 4651,osman.yilmaz@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Tutorials 15 2 30
Preparations before/after weekly lectures 7 9 63
Preparation for midterm exam 2 10 20
Preparation for final exam 1 12 12
Preparing assignments 1 10 10
Preparing presentations 1 20 20
Final 1 4 4
Midterm 1 4 4
TOTAL WORKLOAD (hours) 193

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.1444
LO.2444444
LO.3444
LO.444
LO.54444444
LO.644444
LO.7

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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