COURSE UNIT TITLE

: INTRODUCTION TO MOLECULAR MEDICINE II

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MOT 5026 INTRODUCTION TO MOLECULAR MEDICINE II COMPULSORY 3 0 0 6

Offered By

Molecular Medicine

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR GÜL HÜRAY IŞLEKEL

Offered to

Molecular Medicine

Course Objective

To understand cell behaviour at molecular level, molecular basis of genetic disorders and cancer, stem cell, immunology, genomics, bioinformatics and proteomics.

Learning Outcomes of the Course Unit

1   To describe the cytoskeleton and the roles of cell-cell, cell-ECM and niche on the disease formation and/or progression
2   To have general knowledge about signal transduction and control, cell cycle and cell death.
3   Describes the molecular basis of cancer and immunology.
4   To be able to discuss general concepts of molecular genetics and to describe how to discover disease-related genes.
5   To get know about human stem cells, human genome projects and contributions to medicine.
6   To have general knowledge about bioinformatic databases and their usage.
7   To have general knowledge about genomics, proteomics and their applications.
8   To be able to get and discuss the articles related subject areas.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Heredity, Genes and DNA
2 Replication, Protection, and Regeneration of Genomic DNA
3 RNA synthesis and processing , transcription, regulation of transcription
4 Protein Synthesis, Processing and Regulation-Gene Expression
5 Definition and Types of Mutation, Single Gene Mutations, Polymorphism, Genetic and Epigenetic Control Mechanisms-1
6 Mutation Definition and Varieties, Single Gene Mutations, Polymorphism, Genetic and Epigenetic Control Mechanisms-2
7 Molecular Foundations of Genetic Diseases
8 MID-TERM
9 Hormones; General Properties and Mechanisms of Effect
10 Molecular Basis of Endocrine Diseases
11 Molecular Foundations of Cancer
12 Immunology for Molecular Medicine
13 Molecular Organization in Tissue Level
14 The Basics of Molecular Pharmacology
15 Article Discussion
16 FINAL

Recomended or Required Reading

Textbook(s):
Lodish, Berk, Matsudaira, Kaiser, Krieger, Scott, Zipursky, Darnell , Molecular Cell Biology
Alberts, et al. Molecular Biology of the Cell , Fifth ed., Garland Sciences.
Supplementary Book(s):
Marks Basic Medical Biochemistry, A Clinical Approach. Michael Lieberman, Allan D. Marks
Lehninger Principles of Biochemistry 5th Edition,David L. Nelson, Michael M. Cox.
References:
Materials: Articles and reviews about course subjects.

Planned Learning Activities and Teaching Methods

Course will be performed by a series of presentations which include theriotecal knowledge. It is accepted that students should read about presentation subjects before coming to classroom.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


Further Notes About Assessment Methods

None

Assessment Criteria

Understanding, learning, analyse, compare, actively contribution

Language of Instruction

Turkish

Course Policies and Rules

Actively contribution in class

Contact Details for the Lecturer(s)

e-mail: huray.islekel@deu.edu.tr
Phone: 412 44 08

Office Hours

Tuesday, 12:30-13:30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparation for midterm exam 1 33 33
Preparation for final exam 1 33 33
Preparation before/after weekly lectures 14 3 42
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.15555545455
LO.25555545455
LO.35555545455
LO.45555545455
LO.55555545455
LO.65555545455
LO.7555555545455
LO.85555555555

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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