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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS PER 5007 BIOPHYSICS OF CIRCULATION SYSTEM COMPULSORY 1 2 0 4

Offered By

Perfusion Techniques

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR ERDEM ERINÇ SILISTRELI

Offered to

Perfusion Techniques

Course Objective

introduces Fluid mechanicsand dynamicsofthe circulatory system, basicelectronics,computing techniques, static and dynamiccharacteristics,transducers, andchemicalbiosensors,bloodpressure and bloodflow

Learning Outcomes of the Course Unit

1   Learns thebasicfluid mechanicsand dynamics 2   learns techniques for the calculation offluid dynamics 3   learns transducersforchemical andbiosensors 4   learns Bloodpressure and bloodflow relatedcalculations 5   biophysicaleffectsofcardiopulmonary bypasstechniquesarelearned

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Static and dynamiccharacteristicsof the measurement system. Electricaltheory (Ohm's Law, capacitance): bio-electric potential (electrocardiogram, elektroencephelograph) 2 Bio-electrodes: electrode-electrolyte interface, polarization, potentialmonitoringelectrodes 3 Biosensingelements:enzyme-based biosensors, antibody-based biosensor-s, Nucleicacid-based biosensors, cell-based biosensors 4 transducers: transduction, signal acquisition; Heat transfer; conduction, convection, radiation 5 Biophysicalperceptionelectrodes(surface electrodes, micro-electrodes). Mechanicaltransducers: pressure, flow. 6 Fluiddynamics; "Shear stress" andstress, viscosity,Poiseuille's law, Reynold's number. 7 Biotransport: fluid compartments, concentration, pressure, bodypH,diffusion(self-diffusion, facilitated diffusionand activediffusionandtransport), Ozmosis: osmolarity, tonicity, osmotic pressure, osmolar-meters, membranetransport 8 Midterm Exam 9 Hemodynamics, blood pressure and bloodflowcalculations,areheart soundsandmurmurs. 10 ECG, cardiac catheterization. 11 Medicaland diagnosticimagingtechnologies to: the properties of light, electromagnetic spectrum, electromagnetic (EM)wave energy,the production ofEM radiation 12 Matter-radiation interaction: EM waveabsorption,scatteringofEM waves, image transfer 13 imaging basics;imageacquisition,digitizationof images, rekonsrüksiyo3Dimage, the image quality 14 X-ray,fluoroscopy,DSA,computed tomography,nuclear medicine,ultrasound(echocardiography, doppler flowtransducers), blood pressure monitors,magnetic resonance(MRA, MRI), positron emission tomography (PET).

Recomended or Required Reading

Richard E. Klabunde, Cardiovascular Physiology Concepts; William R. Milnor, Cardiovascular Physiology; John B. Wes, Respiratory Physiology: The Essentials.

Planned Learning Activities and Teaching Methods

PowerPoint presentationsand oral.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 MTE MIDTERM EXAM 2 FIN FINAL EXAM 3 FCG FINAL COURSE GRADE MTE * 0.40 + FIN* 0.60 4 RST RESIT 5 FCGR FINAL COURSE GRADE MTE * 0.40 + RST* 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

Midterm exams,homeworkissues, final exam.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

To be announced.

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 14 1 14 Tutorials 14 2 28 Preparations before/after weekly lectures 14 2 28 Preparation for midterm exam 1 11 11 Preparation for final exam 1 15 15 Final 1 2 2 Midterm 1 2 2 TOTAL WORKLOAD (hours) 100

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 LO.1 5 LO.2 4 4 LO.3 3 4 LO.4 4 4 LO.5 4 3