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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS MBG 5008 CANCER BIOLOGY ELECTIVE 3 0 0 7

Offered By

Molecular Biology and Genetics Master Programme

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASISTANT PROFESSOR CAN KÜÇÜK

Offered to

Molecular Biology and Genetics Master Programme

Course Objective

This course's aim is to discuss the main concepts of cancer biology including but not limited to neoplastic transformation, invasion, metastasis, and to learn about the similarities and differences of different types of recurrent cancers.

Learning Outcomes of the Course Unit

1   To understand the initial molecular mechanisms associated with neoplastic transformation for different types of cancer. 2   To understand the consecutive steps involved in generation of a fully established malignancy. 3   To understand the molecular etiology of different types of malignancies. 4   To know the importance of genetic and epigenetic aberrations in tumorigenesis. 5   To know the popular perspectives of cancer diagnosis, prognosis and therapy.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Introduction-Initiation of cancer and tumor progression 2 Tumor viruses and oncogenes 3 Tumor suppressor genes 4 Growth factors, hormones, cellular receptors pathways 5 DNA repair 6 Cell cycle regulation 7 Apoptosis 8 Cancer stem cell hypothesis 9 Mid term 10 Angiogenesis and Metastasis 11 Epidemiology of cancer 12 Cancer Immunosurveilance and therapy 13 Cancer Genetics and Epigenetics 14 Cancer genomics-I 15 Cancer genomics-II 16 Final Exam

Recomended or Required Reading

Textbook(s): The Biology of Cancer, 2nd edition, Robert A. Weinberg.

Planned Learning Activities and Teaching Methods

1- Taught in lecture 2- Questions and answers 3- Discussion

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 AS Midterm Exam 2 FN Final Exam 3 BNS Final Course Grade roundAS * 0.50+FN*0.50

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

To be announced.

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 14 3 42 Preparations before/after weekly lectures 14 7 98 Preparation for midterm exam 1 12 12 Preparation for final exam 1 12 12 Preparing assignments 2 5 10 Final 1 3 3 Midterm 1 3 3 TOTAL WORKLOAD (hours) 180

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 LO.1 4 2 LO.2 2 LO.3 3 LO.4 3 LO.5 3