COURSE UNIT TITLE

: PROTEIN BIOCHEMISTRY AND BIOTECHNOLOGY

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 5012 PROTEIN BIOCHEMISTRY AND BIOTECHNOLOGY ELECTIVE 3 0 0 7

Offered By

Molecular Biology and Genetics Master Programme

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR MEHMET ÖZTÜRK

Offered to

Molecular Biology and Genetics Master Programme

Course Objective

Proteins, which are one of the important macromolecules for organisms, are used in many fields including medical, pharmacological, food and analytical industries. The structure, engineering, sources and production, purification and characterization of proteins will be discussed within the context of this course. Also, proteins used for therapeutical, analytical purposes and industrial purposes will be evaluated.

Learning Outcomes of the Course Unit

1   Understand three dimensional structure, folding mechanisms, post translational modifications and functions of proteins, and enzyme kinetics.
2   Have knowledge about proteomics and protein engineering.
3   Have knowledge about protein sources, engineering, production, purification and characterization method(s) for the application fields of protein biotechnology.
4   Evaluate the biotechnological importance of proteins in therapeutical, industrial, analytical fields of biotechnology.
5   Determine proper source, production, purification and characterization method(s) of proteins.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to proteins and proteomics
2 Protein structure and enyzme kinetics
3 Protein sources in biotechnology
4 Protein engineering
5 Protein purification and characterization
6 Large-scale protein production
7 Therapeutic proteins: blood products, vaccines and enzymes
8 Therapeutic antibodies
9 Midterm
10 Hormones and growth factors used therapeutically
11 Interferons, interleukins and tumour necrosis factors
12 Proteins used for analytical purposes Industrial enzymes
13 Non-catalytic industrial proteins
14 Homework Presentations: Applications of enyzmes in biotechnology
15 Final Exam
16 .

Recomended or Required Reading

Gary Walsh, Proteins: Biochemistry and Biotechnology, 2nd Edition, Wiley, 2014.

Planned Learning Activities and Teaching Methods

1. Presentation
2. Interactive narrative
3. Question-answer technique
4. Homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 AS Midterm Exam
2 FN Final Exam
3 BNS Final Course Grade roundAS * 0.50+FN*0.50


Further Notes About Assessment Methods

None

Assessment Criteria

Meaningful learning of the basic concepts given in presentations, association of concepts with each other, establishing the cause-result relationships and making comments by using the information available for problems and evaluating idea generation are carried out with mid-term and final exams, active participation to the lecture, homework.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

mehmet.ozturk@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 15 4 60
Preparation for midterm exam 1 20 20
Preparation for final exam 1 25 25
Preparing assignments 1 15 15
Preparing presentations 1 10 10
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 176

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.14
LO.22
LO.32
LO.42
LO.53