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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS MBG 5007 MICROBIAL GENETICS AND GENOMICS ELECTIVE 3 0 0 8

Offered By

Molecular Biology and Genetics Master Programme

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASISTANT PROFESSOR YAVUZ OKTAY

Offered to

Molecular Biology and Genetics Master Programme

Course Objective

To have comprehensive knowledge about the organization and dynamics of bacterial genome.

Learning Outcomes of the Course Unit

1   to explain the structure and organization of bacterial genome 2   to discuss the methods of bacterial genetic analysis 3   to describe the lytic and lysogenic cycles 4   to define terms used in microbial genetics 5   to discuss the mechanisms of regulation of gene expression in bacteria

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 A Brief History of Bacterial Molecular Genetics 2 The Bacterial Chromosome: DNA Structure, Replication, and Segregation 3 Bacterial Gene Expression: Transcription, Translation, and Protein Folding 4 Bacterial Genetic Analysis: Forward and Reverse 5 Plasmids 6 Conjugation 7 Transformation 8 MIDTERM 9 Lytic Bacteriophages: Development, Genetics, and Generalized Transduction 10 Lysogeny: the Paradigm and the Role of Lysogenic Conversion in Bacterial Pathogenesis 11 Transposition, Site Specific Recombination, and Families of Recombinases 12 Molecular Mechanisms of Homologous Recombination 13 DNA Repair and Mutagenesis 14 Regulation of Gene Expression: Operons 15 Global Regulation: Regulons and Stimulons 16 Final Exam

Recomended or Required Reading

Textbook(s)/References/Materials: Textbook(s): Molecular Genetics of Bacteria, 4th Edition, by Larry Snyder, Joseph E. Peters, Tina M. Henkin, and Wendy Champness, ASM Press, 2013 ISBN-13: 978-1555816278 Supplementary Book(s): Brock Biology of Microorganisms, 13th Edition, by Michael T. Madigan, John M. Martinko, David Stahl, and David P. Clark, Benjamin-Cummings, 2010 ISBN: 978-0321649638

Planned Learning Activities and Teaching Methods

Theoretical lectures with PowerPoint

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 AS Midterm Exam 2 FN Final Exam 3 BNS Final Course Grade roundAS * 0.50+FN*0.50

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Yavuz.oktay@deu.edu.tr Phone: 412 6555

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 14 3 42 Tutorials 15 1 15 Preparations before/after weekly lectures 15 4 60 Preparation for midterm exam 1 20 20 Preparation for final exam 1 25 25 Preparing assignments 4 10 40 Midterm 1 2 2 Quiz etc. 0 0 0 Final 1 2 2 TOTAL WORKLOAD (hours) 206

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 LO.1 4 LO.2 3 LO.3 3 LO.4 3 LO.5 3