COURSE UNIT TITLE

: ADVANCED TISSUE REPAIR AND REGENERATION

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
MBG 6113 ADVANCED TISSUE REPAIR AND REGENERATION ELECTIVE 3 0 0 12

Offered By

Molecular Biology and Genetics

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR HATICE GÜNEŞ ÖZHAN BAYKAN

Offered to

Molecular Biology and Genetics

Course Objective

To study basic mechanisms of how cells of different tissues respond to tissue damage or injury
To explore the mechanisms of regeneration in various tissues and organs
To study the main mechanistic differences in injury responses of different organisms
To discuss strategies on how to repair, replace and regenerate various tissues and organs to solve major clinical problems

Learning Outcomes of the Course Unit

1   To understand the fundamental concepts and the basic strategies of repair and regeneration in response to injury in various tissues and organs
2   To distinguish the fundamental differences in regeneration mechanisms and capacities of different models
3   To compare the regenerative capabilities of various organs
4   To understand the concept and importance of stem cells in regeneration
5   To appreciate the potential of stem cells and gain a perspective in stem cell based approaches for regenerative medicine
6   To acquire the ability to access, present and discuss the knowledge on tissue repair and regeneration via scientific articles

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to general concepts 1: cell plasticity, positional memory, types of regenerative capacities of tissues
2 Introduction to general concepts 2: stem cells and types of stem cells
3 Wound healing: Early wound responses to injury
4 Wound healing: Mechanisms of wound closure and healing
5 Heart regeneration
6 Liver regeneration
7 Pancreas regeneration
8 Muscle regeneration/ Mid-term exam
9 Peripheral blood and bone marrow for bone regeneration
10 Kidney and lung regeneration
11 Central nervous system regeneration
12 Spinal cord regeneration
13 Appendage regeneration
14 The potential of stem cells for curative therapy
15 Gene therapy approaches
16 Final Exam

Recomended or Required Reading

Textbook(s): Developmental Biology, 10. Edition. Scott F. Gilbert
Online version: http://10e.devbio.com/
Additional book information will be announced later.
Supplementary Book(s):
References: Helpful reviews on the topics will be shared with students.
Materials:

Planned Learning Activities and Teaching Methods

1. PowerPoint lecture presentations: Lecture subjects will be covered as PowerPoint presentations schematized and simplified for easy visual comprehension.
2. Research article presentation assignment: Students will choose recent research articles about essential or current repair and regeneration related topics, present the key points of the article as a short presentation and discuss those with the audience. All presentations will be held together on a predetermined date outside of lecture hours.

Assessment Methods

Successful / Unsuccessful


*** Resit Exam is Not Administered in Institutions Where Resit is not Applicable.

Further Notes About Assessment Methods

None

Assessment Criteria

Mid-term and final exams: A high percentage (70%) of correct answers, showing that the lecture topics are well digested, is expected.
Oral presentation: The student is expected to understand and present a selected paper, state how well the paper sets forth the scientific question and put forward an idea on future perspectives.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Contact Details for the Instructor: Tel: 412 6557 Mobile: 0531 272 23 99
E-mail: gunesozhan@yahoo.com, gaultw01@gmail.com

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Tutorials 15 2 30
Preparations before/after weekly lectures 15 4 60
Preparation for midterm exam 1 15 15
Preparation for final exam 1 25 25
Preparing assignments 1 30 30
Preparing assignments 1 40 40
Preparing presentations 15 5 75
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 309

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.12
LO.22
LO.32
LO.42
LO.52
LO.62

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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