COURSE UNIT TITLE

: MONOCLONAL ANTIBODY PRODUCTION

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BYM 0506 MONOCLONAL ANTIBODY PRODUCTION ELECTIVE 3 0 0 8

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR ISMET GÜRHAN DELILOĞLU

Offered to

Industrial Ph.D. Program In Advanced Biomedical Technologies

Course Objective

The aim of the course is to give fundamentals of the monoclonal antibody production in pilot and industrial scale and their applications.

Learning Outcomes of the Course Unit

1   Knowledge about the mono-, poly- clonal antibody technology comprehensions.
2   Gaining information about monoclonal antibody production technology in laboratory, pilot and industrial scale

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Structure of antibodies Lecturing
2 Importance,advantages /disadvantages of monoclonal antibodies and Brief history of monoclonal antibody technology Lecturing
3 Techniques of cell cloning Lecturing
4 Monitoring the culture conditions Lecturing
5 In vivo monoclonal antibody production, ethical issues Lecturing
6 In vitro monoclonal antibody production Lecturing
7 Midterm exam Lecturing
8 Identification of monoclonal antibodies, Lecturing
9 Monitoring the culture conditions and Article evaluation Lecturing
10 Pilot scale production Lecturing
11 Large scale production Lecturing
12 Downstream processing, Lecturing
13 Problems and trouble shooting Lecturing
14 Problems and trouble shooting Lecturing

Recomended or Required Reading

Lane, H. D., Antibodies: A Laboratory Manual , Cold Spring Harbour Laboratories, (1988). Shepherd, P., Dean, C., Monoclonal Antibodies: A Practical Approach , Oxfordpress, (2000). Simmons, M. A., Monoclonal Antibodies: New Research , Nova Biomedical Boks, (2005). Zola, H., Monoclonal Antibodies: Preparation and use of Monoclonal Antibodies and Engineered Antibody Derivatives , BiosScientific Pub., (2000).

Planned Learning Activities and Teaching Methods

homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 + ASG * 0.20 + FIN * 0.60
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.20 + ASG * 0.20 + RST * 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof. Dr. S. Ismet Deliloğlu Gürhan

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 12 3 36
Preparations before/after weekly lectures 12 5 60
Preparation for midterm exam 1 35 35
Preparation for final exam 1 45 45
Preparing assignments 1 20 20
Midterm 1 3 3
Final 1 3 3
TOTAL WORKLOAD (hours) 202

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.11524
LO.2525

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

Copyright 2012 DEÜ. BİD

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