COURSE UNIT TITLE

: BAXTERIAL AND VIRAL VACCINES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BYM 0508 BAXTERIAL AND VIRAL VACCINES ELECTIVE 3 0 0 8

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR ISMET GÜRHAN DELILOĞLU

Offered to

Industrial Ph.D. Program In Advanced Biomedical Technologies

Course Objective

Bacterial and viral vaccines in use today and information about production techniques

Learning Outcomes of the Course Unit

1   Understanding the importance of immunization
2   Vaccination principles
3   To explanation of types of vaccine and vaccine production processes
4   Understanding quality control of the vaccines
5   To understand national and international regulations in vaccine production

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Mechanisms of Protection within the Immune System, Basic principles of the vaccines
2 Vaccination and immun response, Adjuvants, Criteria for preparing vaccine strain
3 Introduction to bacterial vaccines Protection against Extracellular Bacteria, Protection against Intracellular Bacteria
4 Classical Bacterial Vaccines, Inactivated Vaccines, Live Vaccines, Introduction to viral vaccines, Classical Viral Vaccines, Inactivated Vaccines, Live Vaccines,
5 Subunit Vaccines and Toxoids (bakteria/virus),
6 Engineering Virus Vectors for Subunit Vaccines (bakteria/virus), Synthetic peptide vaccines,
7 Midterm Exam
8 Live Recombinant Bacterial Vaccines, Recombinant Viral Vaccines, DNA vaccines, Mucosal Vaccines,
9 PassiveVaccination and Antidotes, Plant-based Oral Vaccines
10 Vaccines for Specific Targets, Vaccines against Bioterror Agents and Imperfect Vaccines and the Evolution of Pathogen Virulence,
11 Safety Tests, innocuity (non-infectivity) controls, Immunological safety of the vaccines,
12 Ethical aspects, Laws and Regulations
13 Project presentation
14 Project presentation

Recomended or Required Reading

Anon 1998. Vaccine Supplement. Nature Medicine (Vaccine Supplement 4). Cox, J.C., Coulter, A.R. 1997. Adjuvants_ a classification and review of their modes of action. Vaccine 15, 248-256. Introduction to Modern Virology (6th ed.) by N.J. Dimmock, A.J. Easton, and K.N. Leppard, Blackwell Publishing, 2007. Novel Vaccination Strategies edited by Stefan H. E. Kaufmann, Wiley VCH Verlag GmbH&Co. KGaA, Weinheim, 2004. Spier, R.E. 1998. Ethical aspects of vaccines and vaccination. Vaccine 16, 1788-1794. The World Health Organization web pages on vaccines: http://www.who.int/vaccines Vaccines, (5th ed.), Stanley A. Plotkin, Walter A. Orenstein and Paul A. Offit. W. B. Saunders Company Philadelphia, Pa. ; [London] , 2008.

Planned Learning Activities and Teaching Methods

homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE MTE * 0.40 + FIN * 0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.40 + RST * 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof. Dr. S. Ismet Deliloğlu Gürhan

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 12 3 36
Preparations before/after weekly lectures 12 5 60
Preparation for midterm exam 1 35 35
Preparation for final exam 1 45 45
Preparing assignments 1 20 20
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 200

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.133
LO.223
LO.344
LO.454
LO.521