COURSE UNIT TITLE

: CYTOTOXICITY AND BIOCOMPATIBILITY TESTS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BYM 0614 CYTOTOXICITY AND BIOCOMPATIBILITY TESTS ELECTIVE 2 2 0 9

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR ISMET GÜRHAN DELILOĞLU

Offered to

Industrial Ph.D. Program In Advanced Biomedical Technologies

Course Objective

Providing information about in vitro cytotoxicity and biocompatibility concepts.

Learning Outcomes of the Course Unit

1   Understanding the imporance of the cytotoxicity measurments
2   Understanding the biocompatibility concept
3   Understanding the cell-biomaterial interactions

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 General discription and basic principles
2 Attachment
3 Cytotoxicity Genotoxicity
4 Sensitizasyon
5 Allergy, autoimmunity (Local lymph nodes and popliteal lymph nodes) and irritation
6 Haemocompatibility Laboratory
7 Midterm exam
8 Accumulation and penetration
9 Actual literature survey Laboratory and Regulations
10 Cytotoxicity studies in cancer
11 Pharmaceutical applications of cytotoxicity
12 Aplications in cosmetic production
13 Detection of the biocompatibility of biomaterials Lecturing
14 Detection of the biocompatibility of biomaterials Lecturing

Recomended or Required Reading

1. Cell of Cells: The Global Race to Capture and Control the Stem Cell (Hardcover) by Cynthia Fox (Author), 2007, W.W. Worton&Company Inc. 2. Culture of Animal Cells: A manual of Basic Techniques, by Freshney, I.A., 2005, Wiley-Liss, Inc., New York. 3. Embryonic Stem Cells: A Practical Approach (Practical Approach Series)(Paperback) by Elena Notarianni (Editor), 4.Martin J. Evans (Editor), 2006, Oxford University Press. 4. Handbook of Industrial Cell Culture: Mammalian, Microbial, and Plant Cells (Hardcover) by Victor A. Vinci (Editor), Sarad R. Parekh (Editor), 2003, Humana Press Inc. 5. Mesenchymal Stem Cells: Methods and Protocols (Methods in Molecular Biology) (Hardcover) by Darwin J. Prockop (Editor), Donald G. Phinney (Editor), Bruce A. Bunnell (Editor),2008, Humana Press. 6. Related journals for recent developments.

Planned Learning Activities and Teaching Methods

homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 + ASG * 0.20 + FIN * 0.60
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.20 + ASG * 0.20 + RST * 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof. Dr. S. Ismet Deliloğlu Gürhan

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 12 3 36
Preparations before/after weekly lectures 12 7 84
Preparation for midterm exam 1 40 40
Preparation for final exam 1 50 50
Preparing assignments 1 20 20
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 234

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.1413
LO.2152
LO.3341

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

Copyright 2012 DEÜ. BİD

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