COURSE UNIT TITLE

: INTERFACE TISSUE ENGINEERING

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BMT 0610 INTERFACE TISSUE ENGINEERING ELECTIVE 3 0 0 6

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASISTANT PROFESSOR AYLIN ŞENDEMIR ÜRKMEZ

Offered to

Industrial Ph.D. Program In Advanced Biomedical Technologies

Course Objective

To define interface tissue engineering;to learn physiology and mechanical properties of bone to soft tissue interfaces; to examine the biomaterials that are being used in interface tissue engineering applications; to discuss potential pathways to design appropriate interface tissue engineering applications; to read and summarize related scientific articles and present it in the class.

Learning Outcomes of the Course Unit

1   Describe what is meant by the term "interface tissue engineering (ITE)",
2   Give examples of cell sources and cite their specific characteristics,
3   Give examples of cell sources and cite their specific characteristics,
4   List different strategies to modify and/or design ITE constructs,
5   Describe specific applications of ITE constructs,Define the anatomy, physiology and mechanical properties of different hard and soft tissue interfaces,
6   Read, understand and assimilate papers, publications and lectures pertaining to the field of ITE and have broad understanding of TE research,

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to Interface Tissue Engineering: Basic definition; current scope of development and use in therapeutics and in vitro testing;Introduction to Interface Tissue Engineering: Basic definition; current scope of development and use in therapeutics and in vitro testing;
2 Overview of Biomaterials: metals, ceramics, polymers (synthetic and natural). Biodegradable materials;
3 Tissue culture basics and applications: primary cells, cell lines, sterile techniques, plastics, enzymes,
4 Cell-Matrix interactions on different kinds of matrices;
5 Bone-Cartilage Tissue Engineering: the anatomy and physiology of cartilage and bone tissue as well as mechanical properties of cartilage-bone tissue interface;
6 Bone-Cartilage Tissue Engineering: the current biomaterials and therapeutic techniques for cartilage-bone interface tissue engineering;
7 Bone-Ligament/Tendon Tissue Engineering: the anatomy and physiology of ligament and bone tissue as well as mechanical properties of ligament-bone tissue interface;
8 Bone-Ligament Tissue Engineering: the current biomaterials and therapeutic techniques for ligament-bone interface tissue engineering;
9 Bone-Meniscus Tissue Engineering: the anatomy and physiology of meniscus and bone tissue as well as mechanical properties of meniscus-bone tissue interface;
10 Bone-Meniscus Tissue Engineering: the current biomaterials and therapeutic techniques for meniscus-bone interface tissue engineering;
11 Muscle-Tendon Tissue Engineering: the anatomy and physiology of muscle and tendon tissue as well as mechanical properties of muscle-tendon tissue interface;
12 Muscle-Tendon Tissue Engineering: the current biomaterials and therapeutic techniques for Muscle-tendon interface tissue engineering;
13 Student Presentations;
14 Student Presentations;

Recomended or Required Reading

1. Bernhard Palsson, Sangeeta N. Bhatia, Tissue Engineering , Pearson (2004).
2. Artmann, Gerhard M.; Minger, Stephen; Hescheler, Jürgen, Stem Cell Engineering (Principles and Applications) ,Springer (2011).
3. Scientific articles provided during the semester

Planned Learning Activities and Teaching Methods

Project and exams

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 + ASG * 0.20 + FIN * 0.60
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.20 + ASG * 0.20 + RST * 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

To be announced.

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Reading 14 3 42
Preparation for final exam 1 20 20
Preparation for midterm exam 1 10 10
Design Project 1 30 30
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 148

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.11533
LO.222
LO.31
LO.43
LO.522
LO.6143

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

Copyright 2012 DEÜ. BİD

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