COURSE UNIT TITLE

: CANCER BIOCHEMISTRY

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 6049 CANCER BIOCHEMISTRY ELECTIVE 2 0 0 12

Offered By

Basic Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR HILAL KOÇDOR

Offered to

Basic Oncology
Molecular Medicine

Course Objective

The goals of this course are to introduce the student to the concepts of the mechanisms of carcinogenesis.
The aim of this course is to discuss the general properties, physical, chemical and biological mechanisms, and their roles in metabolism and in the control of metabolism; to analyse cancer kinetics and types of cancer and in addition, evaluate the common cancers using clinical cases.

Learning Outcomes of the Course Unit

1   Synthesizing, analysing with qualitative an quantitative data, interpretation and evaluation of collected information about normal and cancer cells.
2   Identifiable the carcinogens and have expertise in the theorical basis of carcinogenesis.
3   Acquire basic and clinical cancer knowledge and analyse at the critical level the basic principles of cancer cells and cancer biology.
4   Synthesize the knowledge on proliferation, differantiation and apply it to new situations.
5   Creating the scientific report from obtained results and presentation these results as verbal and visual.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction of cancer ,Cancer phenotype
2 Cell cycle and signaling in cancer
3 Carbohyrate metabolism in cancer
4 Amino acid and protein metabolism in cancer
5 Lipid and cholesterol metabolism in cancer
6 Cancer and epigenetic
7 Chemical carcinogens
8 Cytotoxic spies
9 Nutrition in cancer,Vitamins and trace elements in cancer
10 Research methods in cancer
11 Metabolic changes in cancer
12 Presentation

Recomended or Required Reading


1. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
2. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007,
3. Principles of Cancer Biology, Kleinsmith, (2005).
4. Tumor Biology. G.A.Dalglenish M. Browning Cambridge 1996
5. Nelson DL, Cox MM. Lehninger Principles of Biochemistry. Third editon Worth Publishers, New York, 2000.
6. Devlin TM. Texbook of Biochemistry with Clinical Correlations.Fifth edition, Wiley-Liss, New York, 2002.
7. Meisenberg G, Simmons WH. Principles of Medical Biochemistry. Mosby Inc., St. Louis, Missouri, 1998.
8. Baynes J, Dominiczak MH. Medical Biochemistry. Mosby Inc.,London,1999.
9. Marks DB, Marks AD, Smith CM. Basic Medical Biochemistry. A Clinical Approach. Williams & Wilkins, Baltimore, Maryland, 1996.
10. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007,
11. Tumor Biology. G.A.Dalglenish M. Browning Cambridge 1996

Planned Learning Activities and Teaching Methods

The course will be run in an integrated way-winding theory with case discussion. The methods of learning will be interactive.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCGR FINAL COURSE GRADE MTE * 0.30 + PRF* 0.30 + FIN* 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.30 + PRF* 0.30 + RST* 0.40

Further Notes About Assessment Methods

None

Assessment Criteria

Oral presentation: Each student will give an oral presentation based on a current scientific article related to the week s topic.
Final Paper: The final assignment will be to write a grant proposal focusing on the topics that we have covered in class.
A detailed description of the format and expectations will be given to students following the midterm presentation.

Language of Instruction

Turkish

Course Policies and Rules

Cell phones and beepers must be turned off during class.
Late papers will not be accepted unless the student makes prior arrangements with the professor.

Contact Details for the Lecturer(s)


Dokuz Eylül University, Institute of Oncology, Department Of Basic Oncology Inciraltı/ Izmir

Office Hours


Wednesday 14.00-15.00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 30 1 30
Preparation for final exam 15 10 150
Preparation for quiz etc. 1 40 40
Preparing presentations 5 10 50
1 25 25
Final 1 5 5
TOTAL WORKLOAD (hours) 300

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.15
LO.25
LO.35
LO.45
LO.555