COURSE UNIT TITLE

: PROTEIN KINASE C

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
KIM 6062 PROTEIN KINASE C ELECTIVE 3 0 0 7

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR HÜLYA AYAR KAYALI

Offered to

Chemistry
Chemistry

Course Objective

Within the context of this course, it is aimed to investigate in detail protein phosphorylation reactions and kinases, PKC isotypes and identification, the structure and membrane bindig of PKC C1 and C2 domains, the regülation of PKC by membrane, protein interactions and phosphorylation, the downregulation of PKC, the role of PKC in yeasts as well as the spesific role of atypic PKC.

Learning Outcomes of the Course Unit

1   Evaluate protein phosphorylation reactions and protein kinases,
2   Know PKC isotypes and identification,
3   Reclaim the structure and membrane bindig of PKC C1 and C2 domains, the regülation of PKC by membrane, protein interactions and phosphorylation, and the downregulation of PKC,
4   Understand, the role of PKC in yeasts,
5   Gain knowledge about the spesific role of atypic PKC.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to Protein Kinase C
2 Protein Kinase C
3 The structure, function and relation to membrane of PKC C1 domain-1
4 The structure, function and relation to membrane of PKC C1 domain-2
5 The structure and function of C2 domains
6 The regülation of PKC by membrane, protein interactions and phosphorylation
7 MIDTERM
8 The regulation of PKC with membrane interactions
9 The regulation of PKC with phosphorilation-1
10 The regulation of PKC with phosphorilation-2
11 The regulation of PKC with phosphorilation-3
12 The downregulation of PKC
13 The role of PKC in yeasts
14 The spesific role of atypic PKC

Recomended or Required Reading

Dekker, L.V. (ed.), 2004, Protein Kinase C, Plemum Publisher: 191 p.
Kazanietz, M.G. (ed.), 2010, Protein Kinase C in Cancer Signalling and Therapy, Springer, 485 p.

Planned Learning Activities and Teaching Methods

1. Presentation
2. Interactive narrative
3. Question-answer technique
4. Homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40

Further Notes About Assessment Methods

None

Assessment Criteria

Meaningful learning of the basic concepts given in presentations, association of concepts with each other, establishing the cause-result relationships and making comments by using the information available for problems and evaluating idea generation are carried out with mid-term and final exams, active participation to the lecture,homework.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Assoc. Prof. Dr.Hülya Ayar Kayalı
Dokuz Eylül University, Science Faculty, Chemistry Department, Biochemistry Division,
35160, Buca, Izmir, Turkey
Tel: +90 232 3018690
e-mail: hulya.kayali@deu.edu.tr

Office Hours

Wednesday 13.30-15.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 13 3 39
Preparation before/after weekly lectures 13 3 39
Preparation for Mid-term Exam 1 10 10
Preparation for Final Exam 1 20 20
Preparing Group Assignments 2 15 30
Preparing Presentations 2 15 30
Final 1 2 2
Mid-term 1 2 2
TOTAL WORKLOAD (hours) 172

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.13443332545
LO.23443332545
LO.33443332545
LO.434432545
LO.534432545

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

Copyright 2012 DEÜ. BİD

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