COURSE UNIT TITLE

Offered By

Biochemistry

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR GÜL AKDOĞAN

Offered to

Biochemistry
Microbiology
Molecular Medicine

Course Objective

Enzymes are biological catalyzers forming the basis of metabolism. The aim of this course is to discuss the general properties, catalysis mechanisms, and their roles in metabolism and in the control of metabolism; to analyse enzyme kinetics and types of enzyme inhibition and in addition, evaluate the common enzyme defects using clinical cases.
In the practicals related to the course, the following applications will be conducted: enzyme catalysis and inhibition types, monitoring of enzymatic reactions, and the basics of enzyme activity measurements.
In addition, factors effecting blood enzyme activity levels, physiological roles of some selected enzymes, tissue distributions, and clinical reflections and analysis methods will be studied. The up-to-date use of enzyme tests for diagnosis and monitoring of disease and its principles will be discussed. Finally, it will also be noted that enzymes are used as tools for a variety of laboratory tests.

Learning Outcomes of the Course Unit

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Recomended or Required Reading

Main textbook:
1. Harper s Illustrated Biochemistry 28th Edition, 2009 , Murray, Bender, Rotham, Kennelly
Rodwell and Weil.McGraw Hill International Edition.pp51-83.
Supplementary textbooks:
2. Textbook of Biochemistry with Clinical Correlations. Seventh Edition 2011, Thomas M. Devlin. John-Wiley& Sons Inc. Publication, USA , pp. 377-418.
3. Textbook of Clinical Chemistry and Molecular Diagnostics. Eds: Burtis CA, Ashwood ER, Bruns DE, 4th edition, 2006, Elsevier Saunders, St Louis.
4. Newsholme, EA and Leech, TR. Functional Biochemistry in Health and Disease 2010, WILEY-BLACKWELL, Oxford, pp 35-68.
5. Bisswanger, H. Practical Enzymology 2011, WILEY-BLACKWELL.
6. Tietz: Klinik Kimyada Temel Ilkeler Beşinci Baskı. (Editörler: Burtis & Ashwood) (Çeviri Editörü: Diler Aslan).PALMY yayıncılık, pp.352-387.

Planned Learning Activities and Teaching Methods

The course will be run in an integrated way-winding theory with case discussion and laboratory practicals. The methods of learning will be interactive.

Assessment Methods

Further Notes About Assessment Methods

None

Assessment Criteria

Optional, if the instructor needs to add some explanation or further note, this column can be selected from the DEBIS menu.

Language of Instruction

Turkish

Course Policies and Rules

The student is expected to read the resources before coming to class. In addition, he/she is expected to contribute actively to discussion, group-work and practicals. Attending in at least 70 percent of lectures and in at least 80 percent of practicals are mandatory. Plagiarism of any type will result in disciplinary action.

Contact Details for the Lecturer(s)

Gül Güner Akdoğan:
Phone: 412 44 03
GSM: + 533 749 17 96

Office Hours

Mondays 12.30-13.30

Work Placement(s)

None

Workload Calculation

Contribution of Learning Outcomes to Programme Outcomes